Target-tracking system in the stereotactic radiation therapy for body tumors

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(1) Four-dimensional lung cancer imaging has been successfully performed by using a multi-detector CT(2) Real-time fluoroscopic tumor imaging has been achieved by using a flat panel detector for MV x-ray.(3) A kilovolt x-ray CT imaging technique has been developed by using radiotherapy machine.(4) A respiratory curve has been derived from the patient diaphragm position obtained by kilovoltage x-ray imaging.(5) A technique for in-treatment kV cone beam CT imaging has been established.(6) A method for measuring patient set-up errors has been developed for stereotactic radiotherapy immediately before treatment, during treatment, and immediately after treatment. Clinical study has also been launched.(7) A real-time tumor tracking system has been developed by detecting the tumor position estimated from the patient diaphragm position using in-treatment kV x-ray imaging.(8) As for clinical application of large bore CT for radiotherapy. We have applied a 90 cm bore CT to radiotherapy practice.(9) A tumor tracking algorithm has been developed by increasing MW maximum leaf speed.(10) Intensity modulated arc therapy has been achieved by successfully controlling dose rate and gantry speed.(11) We have addressed a problem and proposed a solution to apply previously developed x-band linac to radiotherapy practice.(12) Real-time tumor tracking using robot arm-mounted linac has been studied from a robot engineering view.(13) We have designed a next-generation tracking system by combining a linac with a robot arm and a CT imager.(14) The target and risk organs have been localized immediately before treatment, during treatment and immediately after treatment by using built-in CT imaging unit.(15) We have discovered that commercially available drug serves as a radiosensitizer, and have revealed its radiobiological mechanism.(16) Total assessment and clinical application We have obtained significant treatment outcome by applying our results to clinical practice.