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Research on emotional monitoring in children with severe motor and intellectual disabilities

严重运动和智力障碍儿童情绪监测研究

基本信息

批准号：
17530684
负责人：
TAKEDA Kazunori
金额：
$ 2.44万
依托单位：
University of Tsukuba
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2005
资助国家：
日本
起止时间：
2005 至 2007
项目状态：
已结题

项目摘要

Children with severe motor and intellectual disabilities have a difficult time expressing emotions; therefore, emotional changes are predominantly assessed subjectively, based on the experiences and observations of people around them. In the present study, the emotional changes in children with severe motor and intellectual disabilities were assessed by quantifying levels of alpha-amylase, a salivary digestive enzyme. The study was designed to clarify the following two points: 1) the relationship of salivary amylase to distress caused by medical procedures, and its significance; and 2) the possibility of using salivary amylase as a parameter for assessing the effects of education and therapy in children with severe motor and intellectual disabilities. The results showed that among children with severe motor and intellectual disabilities the activity of salivary amylase strongly reflected the degree of distress caused by medical procedures. Furthermore, the activity of salivary amylase … More was markedly affected by the activity of the sympathetic nervous system. Snoezelen is one of the treatments that aim to relax children with severe motor and intellectual disabilities, and objective assessments of eustress (comfortable stress) proved that the activity of salivary amylase reflected the level of eustress. Lastly, the effects of educational interventional measures were assessed in children with grave motor and intellectual disabilities in whom emotional changes and body movements are difficult to assess due to extremely severe disabilities, and educational interventions caused significant real time changes in the activity of salivary amylase.The results of the present study suggest that salivary amylase may be a useful biomarker for estimating the psychological status of children with severe motor and intellectual disabilities. In addition, the portable test strip salivary amylase activity monitor was a superior technique for assessing the psychological status of children with severe motor and intellectual disabilities. The results of the present study have been reported in two English papers and two Japanese papers and at nine domestic and one overseas academic conventions. These findings suggest that salivary amylase analysis is useful in research on children with severe motor and intellectual disabilities and should contribute to improving their QOL. Less

患有严重运动和智力残疾的儿童很难表达情绪;因此，情绪变化主要是根据周围人的经验和观察主观评估的。在本研究中，通过定量α-淀粉酶（一种唾液消化酶）水平来评估严重运动和智力残疾儿童的情绪变化。该研究旨在阐明以下两点：1）唾液淀粉酶与医疗程序引起的痛苦的关系及其意义; 2）使用唾液淀粉酶作为评估严重运动和智力残疾儿童教育和治疗效果的参数的可能性。结果表明，在严重运动和智力残疾的儿童中，唾液淀粉酶的活性强烈反映了医疗程序所造成的痛苦程度。此外，唾液淀粉酶活性 ...更多信息明显受到交感神经系统活动的影响。Snoezelen是一种旨在放松患有严重运动和智力残疾的儿童的治疗方法，对eustress（舒适压力）的客观评估证明唾液淀粉酶的活性反映了eustress的水平。最后，评估了教育干预措施在严重运动和智力残疾儿童中的效果，这些儿童由于极其严重的残疾而难以评估情绪变化和身体运动，本研究的结果表明，唾液淀粉酶可能是一个有用的生物标志物，用于估计心理状况，有严重运动和智力残疾的儿童。此外，便携式试纸唾液淀粉酶活性监测仪是评估严重运动和智力残疾儿童心理状况的一种上级技术。本研究的结果已发表在两篇英文论文和两篇日文论文以及九个国内和一个国外学术会议上。这些结果表明，唾液淀粉酶分析是有用的研究，对儿童有严重的运动和智力残疾，并应有助于改善他们的生活质量。少