Establishment of diagnostic criteria of cardiac diseases in the cases of sudden infant death

婴儿猝死心脏病诊断标准的建立

• 批准号: 18590627
• 负责人: NISHIDA Naoki
• 金额: $ 2.53万
• 依托单位: University of Toyama (2007)Akita University (2006)
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2006
• 资助国家: 日本
• 起止时间: 2006 至 2007
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18590627/
• 关键词: sudden infant death; heart; cardiac conduction system; medullary arcuate nucleus; prone positioned sleeping; 免疫染色; 心筋疾患; 心奇形; 画像解析

Twenty four cases of sudden infant death under lyear old were examined systematically. Five of 24 cases showed macroscopic cardiac abnormality, which were total anomalous pulmonary venous connection (1 cases), aneurysm of sinus valsalva (2 cases), and coactation of aorta (2 cases). In a case of aneurysm of sinus valsalva showed also atrial septal defect and patatent ductus arteriosus. In microscopically, two cases showed hypertrophic cardiomyopathy, and focal myocardial infarction, respectively, and a case of rheumatic myocarditis, cytomegello myocarditis, was found respectively. In cardiac conduction system, 12 cases showed anomalous accessory connection,. Eleven of 24 cases showed aplasty or hypoplasty of medullary arcuate nucleus, and 8 of 12 cases had anomalous accessory connection in conduction system. And also, 7 cases showed all 3 factors which are brain stem abnormality, prone positioned sleeping, cardiac abnormality, and 6 cases showed 2 kind of abnormal findings. Our results showed overlapping of abnormalities of sleeping position with silent cardiac and brain stem abnormalities have the additional risk of sudden infant death.

本文对24例1岁以下婴儿猝死进行了系统检查。24例心脏肉眼可见异常5例，其中完全性肺静脉异位引流1例，主动脉窦瘤2例，主动脉缩窄2例。1例窦瘤，Valsalva同时显示房间隔缺损和动脉导管未闭。镜下表现为肥厚型心肌病2例，局灶性心肌梗塞2例，风湿性心肌炎1例，细胞心肌炎1例。心传导系统异常旁路12例。24例中11例表现为延髓弓状核成形性或成形性减退，8例为传导系统异常旁路连接。脑干异常、俯卧位睡眠、心脏异常3种因素均有7例，2种异常6例。我们的结果表明，睡眠姿势异常与沉默的心脏和脑干异常重叠有额外的婴儿猝死风险。

项目成果

Indication and limitations of using palatal rugae for personal identification in edentulous cases

无牙颌病例中使用腭皱进行个人识别的适应症和局限性

• 发表时间: 2008
• 期刊: Forensic Sci Int 176
• 作者: Ohtani M;Nishida N;et. al.
• 通讯作者: et. al.

Indication and limitations of using palatal rugae for personal identi fication in edentulous cases.

无牙颌病例中使用腭皱进行个人识别的适应症和局限性。

• 发表时间: 2008
• 期刊: Forensic Sci Int. 176
• 作者: Ohtani M;Nishida N;et. al.
• 通讯作者: et. al.

The sudden and unexpected death of a female-to -male trasnssexual patient

一名女变男的变性患者突然意外死亡

• 发表时间: 2008
• 期刊: J Forensic and Legal, Med 14
• 作者: Inoue H;Nishida N.;et. al.
• 通讯作者: et. al.

sudden and unexpected death of a female-to -male trasnssexual patient

一名女变男的变性患者突然意外死亡

• 发表时间: 2007
• 期刊: J Forensic and Legal Med 14
• 作者: Inoue;H.;Nishida;N.;Ikeda;N.;Tsuji;A. Kudo;K.;Hanagama;M
• 通讯作者: M

Overlapping of pathological abnormality of cardiovascular and central nervous system in the cases of sudden infant death with prone-positioned sleeping.

婴儿猝死与俯卧位的心血管和中枢神经系统病理异常重叠。

• 发表时间: 2006
• 作者: Ohtani M;Nishida N.;et. al.;Nishida N
• 通讯作者: Nishida N