Proteomic analysis of the invading mechanism of Neospora caninum and development of novel preventive and treatment methods

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The aims of this study were to widen our view on the global expression of protein profile of Neospora caninum parasite and to discover vaccine and drug target molecules for control of neosporosis. Approximately 600 protein spots were detected on 2-DE, and 60 proteins were identified by MALDI-TOF-MS analysis. Some of the identified proteins were predicted to be involved in the invasion of the parasite into the host cells and in parasite metabolism. Therefore, some of these proteins could be potential vaccine candidates and drug targets.