Identification of candidate genes for unique QTL affecting growth and obesity discovered from a genetic resource of the wild mouse
Identification of candidate genes for unique QTL affecting growth and obesity discovered from a genetic resource of the wild mouse
批准号:
19380156
负责人:
ISHIKAWA Akira
金额:
$12.73万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2009
中文摘要
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英文摘要
We have previously discovered a new QTL for growth and obesity on mouse chromosome 2 from a gene pool of the wild mouse and have constructed a congenic strain carrying the QTL allele derived from the wild mouse. In this study, we developed many subcongenic strains with different introgressed intervals using the previously constructed congenic strain. Phenotypic characterization of the subcongenic strains developed and expression analyses of genes within the introgressed region revealed that four genes are most likely candidates for the obesity QTL.
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量的形質変異の遺伝的基盤の複雑さ一マウス成長形質のQTL解析からの報告-
数量性状变异遗传基础的复杂性:小鼠生长性状 QTL 分析报告。
DOI:
--
发表时间:
2008
期刊:
動物遺伝育種研究 36巻
影响因子:
--
作者:
[Ishikawa, A., 石川明]
通讯作者:
石川明
野生マウスに発見されたヘテローシスを示す体重QTL
野生小鼠中发现的表明杂种优势的重量 QTL
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[石川明, 並河鷹夫]
通讯作者:
並河鷹夫
Development and characterization of a congenic strain carrying Pbwg12, a growth QTL on mouse chromosome 12
携带 Pbwg12(小鼠 12 号染色体上的生长 QTL)的同系品系的开发和表征
DOI:
--
发表时间:
2010
期刊:
Exp. Anim. 59巻
影响因子:
--
作者:
[Ishikawa, A., Li, C.]
通讯作者:
C.
マウス第12染色体上の体重QTLを導入したコンジェニック系統の樹立とその特徴解析
小鼠12号染色体体重QTL同源品系的建立及特性分析
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[李春, 並河鷹夫, 石川明]
通讯作者:
石川明
マウスの体重変異に関わる遺伝的基盤の解明を目指して
旨在阐明小鼠体重变化的遗传基础
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Mollah, Md. B.R.、Ishikawa, A., 李春・石川明, 石川明]
通讯作者:
石川明
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Establishment of a novel mutant mouse strain showing age-related pigmentation and epigenetic changes in the age-related pigmentation
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Analysis of candidate genes for heterotic QTL discovered from a gene pool of wild mice
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Platinum-group element behavior during partial melting of mantle and a reevaluation of primitive upper mantle estimates
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Development and characterization of congenic strains for new body weight QTLs derived from wild mice
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依托单位:
AN ABDUCTIVE APPROACH TO DISCOURSE UNDERSTANDING USING TENSE AND OLD-NEW INFORMATION AND ITS APPLICATION TO NI-BASED TROUBLESHOOTERS
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海外基金