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Differentiation-induction therapy with adipocytokine for cutaneous squamous cell carcinoma

Differentiation-induction therapy with adipocytokine for cutaneous squamous cell carcinoma
脂肪细胞因子分化诱导治疗皮肤鳞状细胞癌
批准号：
19790791
负责人：
INOUE Takuya
金额：
$2.4万
依托单位：
Saga University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Young Scientists (B)
财政年份：
2007
资助国家：
日本
项目状态：
已结题
起止时间：
2007 至 2009
来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19790791/
关键词：
皮膚腫瘍学分化誘導療法皮膚癌adiponectinadionectinadipocytokine

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英文摘要
We have shown that subcutaneous adipocytes of rats facilitate the differentiation of squamous cell carcinoma cells of the skin in vitro. We hypothesized that adipocyte-derived cytokines have a promoting effect on differentiation of carcinoma cells. We examined the effect of adiponectin on squamous cell carcinoma cells of the skin and investigated the role of adipocytokine on the growth and differentiation of the cancer cells.
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