Research for the effects of toluene exposure on the development and sexual differentiation of the brain

我们最近关注接触环境化学品对儿童健康产生不利影响的风险。这项研究旨在确定发育过程中暴露于甲苯（一种广泛用作工业溶剂的挥发性有机化合物）对大脑性别分化的影响。结果发现，发育期间接触甲苯可降低胎雄性大鼠血睾酮水平和成年期雄性大鼠性二态核SDN-POA的体积。

We recently pay attention to the risk of the adverse effects of environmental chemical exposure on child health. This study was aimed to determine the effects of developmental exposure to toluene, a volatile organic compound widely used as an industrial solvent, on the sexual differentiation of the brain. As the results, it was found that exposure to toluene during developing period decreased blood testosterone levels of fetal male rats and the volume of the SDN-POA, a sexually dimorphic nucleus, of male rats in adulthood.