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Development of DNA/chitosan/lipid complex multi-layer membrane for GTR, GBR

Development of DNA/chitosan/lipid complex multi-layer membrane for GTR, GBR
GTR、GBR用DNA/壳聚糖/脂质复合物多层膜的开发
批准号:
19592277
负责人:
INOUE Yusuke
金额:
$2.83万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2009

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项目成果

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中文摘要
翻译
研究了由DNA、壳聚糖和两亲性脂类制成的实验多层膜的特性。并对市售DNA/壳聚糖/脂质复合膜或GTR膜或钛板上形成多层膜的可能性进行了研究。DNA/壳聚糖/脂质复合多层膜对牙龈卟啉单胞菌和金黄色葡萄球菌具有抗菌活性,对白色念珠菌具有抗真菌活性。DNA/壳聚糖/脂复合膜或GTR膜上形成了DNA/壳聚糖/脂复合膜多层膜,显示出抗菌和抗真菌活性。
英文摘要
The characteristics of experimental multi-layer GTR or GBR membrane made from DNA, chitosan and amphiphilic lipid was investigated. And also the possibility of multi-layer formation on the DNA/chitosan/lipid complex film or GTR membrane on the market or titan plate was investigated. DNA/chitosan/lipid complex multilayer membrane showed antibacterial activity against Porphyromonas gingivalis and Staphyrococcus aureus, and antifungal activity against Candida albicans. The DNA/chitosan/lipid complex multilayer formed on the DNA/chitosan/lipid complex film or GTR membrane, and showed antibacterial activity and antifungal activity as DNA/chitosan/lipid complex multilayer membrane showed.
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