Development of light-cured bonding a gent which bond to polished dentin

开发出可与抛光牙本质粘合的光固化粘合剂

• 批准号: 09672030
• 负责人: INOUE Yusuke
• 金额: $ 1.92万
• 依托单位: FUKUOKA COLLEGE OF HEALTH SCIENCES
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1997
• 资助国家: 日本
• 起止时间: 1997 至 1998
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-09672030/
• 关键词: bonding; polished dentin; light-cured bonding agent; self-etching primer; セルフェッチングプライマー

I had developed the new bonding system with the self-etching primer containing 2-acryloyloxyethyl hydrogen maleate (2AEC) or 2-acryloyloxyethyl hydrogen citraconate (2AEC), and N-methylolacrylamide (MEAA), It produced high bond strength of light-cured bonding system on the market. From these results, I thought it was possible to develop the new light-cured bonding agent which was mixed with adhesive monomers (2-methacryloyloxyethyl hydrogen maleate : 2MEM, and 2-methacryloyloxyethyl hydrogen succinate : 2MES) and self-etching primer.The sixty light-cured bonding agents were prepared by adding 2MEM(1, 5,10 wt %) or 2MES (1, 5 wt %) or BisGMA (1 wt %) to various self-etching primers containing water, 2AEM or 2AEC, and MEAA or HEMA.The bond strength of the new light-cured bonding agents were ranged from about 3 MPa to about 16 MPa. Especially, the bond strength of light-cured bonding agents containing 2AEM or 2AEC, MEAA, and 2MEM showed higher than other light-cured bonding agents.Although, the long term water immersion (1 month, 3 months, 6 months) did not reduce the bond strength of light-cured bonding agents which showed high bond strength after 24 hours water immersion, a hundred thousand therma cycling from 4ﾟC to 60ﾟC reduced the bond strength.

研制了含有顺丁烯二酸异丙酯(2AEC)或柠檬酸氢氧乙酯(2AEC)和N-羟甲基丙烯酰胺(MEAA)的自酸蚀粘接体系，市场上的光固化粘接体系具有较高的粘接强度。根据这些结果，我认为有可能开发出一种新的光固化粘结剂，它与粘接单体(2-甲基丙烯酰氧乙基马来酸氢酯：2MEM和2-甲基丙烯酰氧乙基丁二酸氢酯：2MES)和自酸蚀底漆混合。将2MEM(1，5，10wt%)或2MES(1，5wt%)或BisGMA(1wt%)添加到各种含水、2AEM或2AEC以及MEAA或HEMA的自酸蚀底漆中，制备了60种光固化粘结剂，粘接强度在3~16 Mpa之间。尤其是含有2AEM或2AEC、MEAA和2MEM的光固化粘结剂的粘结强度高于其他光固化粘结剂，但长期浸水(1个月、3个月、6个月)不会降低光固化粘结剂的粘结强度，浸水24小时后粘结强度较高，但从4ﾟC到60ﾟC循环10万热会降低粘结强度。

项目成果

T.Fukushima,T.Itoh,Y,Inoue et al: "Effect of dentin primers containing N-methylolacrylamide or N-methylolmethacylamide on dentin pretreatment" Journal of Dentistry. in press.

T.Fukushima，T.Itoh，Y，Inoue等：“含有N-羟甲基丙烯酰胺或N-羟甲基甲基丙烯酰胺的牙本质引物对牙本质预处理的影响”牙科杂志。

T.Fukushima, T.Itoh, Y.Inoue, M.Kawaguchi, K.Miyazaki: "Effect of dentin primers containing N-methylolacrylamide or N-methylolmethacrylamide on dentin pretreatment" Journal of Dentistry. (IN PRESS).

T.Fukushima、T.Itoh、Y.Inoue、M.Kawaguchi、K.Miyazaki：“含有 N-羟甲基丙烯酰胺或 N-羟甲基甲基丙烯酰胺的牙本质引物对牙本质预处理的影响”牙科杂志。