植物細胞サイズの転写制御

为了了解GT-2型三螺旋转录因子家族在细胞分化和器官发生中的分子功能，我在拟南芥根系中进行了细胞类型特异性转录谱分析和全基因组染色质结合测定。对这些大数据集的数据分析清楚地显示了属于不同激素信号通路的基因的丰富。此外，我能够利用这些基因家族成员的功能缺失等位基因组合的代表性分子标记直接在拟南芥植物中证实初步结果。在未来，我将利用遗传、生理和分子方法进一步研究这一新的功能联系。

In order to understand the molecular function of the GT-2 type trihelix transcription factor family for cell differentiation and organogenesis, I have carried out cell type-specific transcriptional profiling and genome-wide chromatin binding assays in Arabidopsis roots. The data analysis of these large data sets clearly show an enrichment of genes which belong to distinct hormonal signaling pathways. In addition, I was able to confirm the preliminary results directly in Arabidopsis plants using representative molecular markers in combinations of loss-of-function alleles of those gene family members. In the future, I will further investigate this novel functional link using genetic, physiological and molecular approaches.