植物細胞サイズの転写制御

为了了解GT-2型三螺旋转录因子家族在细胞分化和器官发生中的分子功能，我在拟南芥根中进行了细胞类型特异性转录图谱和全基因组染色质结合分析。对这些大型数据集的数据分析清楚地表明，属于不同荷尔蒙信号通路的基因丰富了。此外，我能够使用具有代表性的分子标记在这些基因家族成员的功能丧失等位基因组合中直接确认在拟南芥植物中的初步结果。在未来，我将使用遗传学、生理学和分子方法进一步研究这种新的功能联系。

In order to understand the molecular function of the GT-2 type trihelix transcription factor family for cell differentiation and organogenesis, I have carried out cell type-specific transcriptional profiling and genome-wide chromatin binding assays in Arabidopsis roots. The data analysis of these large data sets clearly show an enrichment of genes which belong to distinct hormonal signaling pathways. In addition, I was able to confirm the preliminary results directly in Arabidopsis plants using representative molecular markers in combinations of loss-of-function alleles of those gene family members. In the future, I will further investigate this novel functional link using genetic, physiological and molecular approaches.