Regulatory mechanisms of meiotic recombination through movements and morphogenesis of chromosomes

同源重组在减数分裂期间染色体分离以及基因组多样性的产生中起作用。减数分裂重组与称为联会复合体的独特染色体结构的形成相结合。不仅形成独特的染色体结构，而且减数分裂显示染色体运动和细胞核内染色体的重排。在这项研究中，我们表明，联会复合体的形成和染色体运动的核膜蛋白，Mps3的磷酸化调节。这表明核膜在染色体功能方面的新作用。

Homologous recombination plays a role in chromosome segregation during meiosis as well as production of genome diversity. Meiotic recombination is coupled with the formation of an unique chromosome structure referred as to the Synaptonemal complex. Not only the formation of the unique chromosome structures, but also meiosis shows chromosome motion and rearrangement of chromosomes inside a nucleus. In this study, we showed that the formation of synaptonemal complex and chromosome motion is regulated by phosphorylation of a nuclear envelope protein, Mps3. This suggests the novel role of nuclear envelop in respect of chromosome functions.