The study on mycotoxin detoxification and protection of animal mycotoxicoses in Thaoland.

陶兰地区霉菌毒素解毒及动物霉菌中毒防护研究.

• 批准号: 20405042
• 负责人: KUMAGAI Susumu
• 金额: $ 11.07万
• 依托单位: The University of Tokyo
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2008
• 资助国家: 日本
• 起止时间: 2008 至 2010
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20405042/
• 关键词: アフラトキシン; ゼアラレノン; タイ; 家畜; 分解

In order to find metabolic detoxification by micro-organisms in soil of Thailand, where heavy contamination with mycotoxins has been observed, bacteria and fungi isolated from Cassava farms in Thailand were examined for their activities to metabolize aflatoxin, ochratoxin A and zearalenone. The result demonstrated some bacteria and fungi to metabolize aflatoxin B1 and ochratoxin A. Feces of horse, sheep and pig living in the central region of Thailand, and anaerobic bacteria isolated from the feces, were also examined for their metabolic activities toward mycotoxins, but clear metabolism was not found. With regard to animal tissues, a possible conversion of aflatoxin B2 to B1 by the liver tissues from various animals was suggested. Also tissues of various organs of goat were demonstrated to metabolize zearalenone to alpha-and beta-zearalenols.

为了在泰国土壤中发现微生物的代谢解毒，已经观察到了对霉菌毒素的严重污染，从泰国的木薯农场分离出的细菌和真菌，检查了其可代谢性黄于洛霉素A和玉米蛋白A和Zearalenone的活动。结果表明，一些细菌和真菌可代谢黄曲霉毒素B1和ochratoxin A.居住在泰国中部地区的马，绵羊和猪的粪便，以及从粪便中分离出来的厌氧菌，还检查了它们的代谢活性，但尚未发现清晰的代谢性活性。关于动物组织，建议通过各种动物的肝组织将黄曲霉毒素B2转化为B1。还证明，各种山羊器官的组织也将Zearalenone代谢为α-二糖烯醇。

项目成果

Determination of Organothins in human breast milk by gas chromatography with flame photometric detection.

采用气相色谱火焰光度检测法测定人母乳中的有机素。

• 发表时间: 2008
• 期刊: J.Health Science 54
• 作者: Mino;Y.;Amano;F.;Yoshioka;T.;Konishi;Y.
• 通讯作者: Y.

The toxic effects and fate of intravenously administered zearalenone in goats

• DOI: 10.1016/j.toxicon.2009.10.004
• 发表时间: 2010-02-01
• 期刊: TOXICON
• 影响因子: 2.8
• 作者: Dong, M.;He, X. J.;Kumagai, S.
• 通讯作者: Kumagai, S.

Determination of a yellow rice toxin, luteoskyrin, in rice by using liquid chromatography-tandem mass spectrometry with electrospray ionization.

• DOI: 10.4315/0362-028x-72.6.1321
• 发表时间: 2009-06
• 期刊: Journal of food protection
• 影响因子: 2
• 作者: Kohei Mizutani;S. Kumagai;N. Mochizuki;Y. Kitagawa;Y. Sugita‐Konishi

Enumeration of Fungi in Fruits by the Most Probable Number Method.

用最可能数法对水果中的真菌进行计数。

• 发表时间: 2010
• 期刊: J Food Sci. 75(9)
• 作者: Watanabe M;Tsutsumi F;Lee KI;Sugita-Konishi Y;Kumagai S;Takatori K;Hara-Kudo Y;Konuma H
• 通讯作者: Konuma H

Distribution and residue depletion of oxytetracycline in giant freshwater prawn (Macrobrachium rosenbergii).

土霉素在巨型淡水虾（罗氏沼虾）中的分布和残留消耗。

• 发表时间: 2008
• 期刊: Journal of Food Protection 70
• 作者: Poapolathep;A.;Poapolathe P;S.;Imsilp;K.;Wannapat;N.;Klangkaew;N.;Kusutjarit;N. and Kumagai;S.
• 通讯作者: S.