Population genetics analysis of Plasmodium vivax-infected erythrocyte surface protein PvSTP
Population genetics analysis of Plasmodium vivax-infected erythrocyte surface protein PvSTP
批准号:
20406009
负责人:
KANEKO Osamu
金额:
$10.9万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
在转录和翻译水平上,间日疟原虫PvSTP2的表达比PvSTP1更丰富。PvSTP2位于寄生虫感染的红细胞表面,与寄生虫感染的红细胞膜下观察到的Schuffner点、点状结构共存。在PvSTP1基因座上检测到阳性的多样性选择,许多间日疟患者存在PvSTP1或PvSTP2抗体。
英文摘要
Plasmodium vivax PvSTP2 was detected more abundantly than PvSTP1 at the transcription and translation level. PvSTP2 was located on the parasite-infected erythrocyte surface and colocalized with a Schuffner's dots, dot-like structure observed beneath the parasite-infected erythrocyte membrane. Positive diversifying selection was detected on PvSTP1 gene locus and many Vivax malaria patients possessed antibodies against PvSTP1 or PvSTP2.
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Antibody response to Plasmodium vivax Subtelomeric Transmembrane Protein (PvSTP), a homolog of Plasmodium falciparum SURFIN, in P. vivax-infected patients
间日疟原虫感染患者对间日疟原虫亚端粒跨膜蛋白 (PvSTP)(恶性疟原虫 SURFIN 的同源物)的抗体反应
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Sungkapong T, Yahata K, Culleton R, Tsuboi T, Ruengveerayuth R, Ruengveerayuth R, Sattabongkot J, Udomsangpetch R, Kaneko O, Chotivanich K.]
通讯作者:
Chotivanich K.
Diversity of Plasmodium falciparum SURFIN_<4.2> in Thai field isolates
泰国野外分离株中恶性疟原虫 SURFIN_<4.2> 的多样性
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Kaewthamasorn M, Yahata Y, Alexandre JSF, Nakazawa S, Torii M, Sattabongkot J, Udomsangpetch R, Kaneko O]
通讯作者:
Kaneko O
Antibody Responses to Plasmodium vivax Subtelomeric Transmembrane Protein (PvSTP), a Homolog of Plasmodium falciparum SURFIN, in P.vivax-infected Patients
间日疟原虫感染患者对间日疟原虫亚端粒跨膜蛋白 (PvSTP)(恶性疟原虫 SURFIN 的同源物)的抗体反应
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Sungkapong T, Yahata K, Culleton R, Tsuboi T, Torii M, Ruengveerayuth R, Sattabongkot J, Udomsangpetch R, Kaneko O, Chotivanich K]
通讯作者:
Chotivanich K
マラリア原虫の赤血球侵入・感染赤血球表面の生物学
疟疾寄生虫对红细胞的侵袭和受感染红细胞表面的生物学
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Hayashi T, Yokote K, Saito Y, Iguchi A., 金子修]
通讯作者:
金子修
Plasmodium vivax subtelomeric transmembrane protein 2 (PvSTP2), a homolog of P. falciparum SURFIN : transcription and localization
间日疟原虫亚端粒跨膜蛋白 2 (PvSTP2),恶性疟原虫 SURFIN 的同源物:转录和定位
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Ishida, H., Matsuzaki-Moriya, C., Imai, T., Yanagisawa, K., Nojima, Y., Suzue, K., Hirai, M., Iwakura, Y., Yoshimura, A., Hamano, S., Shimokawa, C., Hisaeda, H., 金子修]
通讯作者:
金子修
共 19 条
Signaling mechanism of the apical organelle discharge by malaria parasites during erythrocyte invasion
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批准号:19H03461
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.15万
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财政年份:2019
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负责人:KANEKO Osamu
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依托单位:
Development of a live attenuated monkey malaria vaccine with enhanced antigenicity
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批准号:17K19566
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项目类别:Grant-in-Aid for Challenging Research (Exploratory)
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资助金额:$4.16万
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财政年份:2017
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负责人:KANEKO Osamu
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依托单位:
Signaling in malaria parasites during erythrocyte invasion
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批准号:16H05184
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.23万
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财政年份:2016
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负责人:KANEKO Osamu
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依托单位:
Molecular basis of the adaptation of Plasmodium knowlesi to human erythrocytes using mutator parasite lines
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批准号:15K15125
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.41万
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财政年份:2015
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负责人:KANEKO Osamu
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依托单位:
Deciphering hypnozoite formation of Plasmodium vivax
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批准号:15H02656
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$26.96万
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财政年份:2015
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负责人:KANEKO Osamu
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依托单位:
Mechanism of the tropism switching of monkey malaria to human using Plasmodium knowlesi mutator line
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批准号:25670203
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.5万
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财政年份:2013
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负责人:KANEKO Osamu
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依托单位:
Signal transduction during erythrocyte invasion by malaria parasites
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批准号:25293102
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.15万
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财政年份:2013
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负责人:KANEKO Osamu
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依托单位:
Seroepidemiology of the molecules expressed on the Plasmodium vivax-infected erythrocyte surface
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批准号:24406012
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.32万
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财政年份:2012
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负责人:KANEKO Osamu
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依托单位:
Genetic manipulation to generate transgenic Plasmodium vivax invasive to the mature erythrocytes
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批准号:23659215
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.41万
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财政年份:2011
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负责人:KANEKO Osamu
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依托单位:
Identification and targeting of the functional domains of malaria parasite's molecules involved in the erythrocyte invasion
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批准号:22390079
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.06万
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财政年份:2010
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负责人:KANEKO Osamu
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依托单位:
Design of data-driven lumped parameter canonical controller for distributed parameter system with its performance analysis
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批准号:22560442
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.66万
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财政年份:2010
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负责人:KANEKO Osamu
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依托单位:
On MPUM theory for dynamical systems defined by the rings : Kernel representation approach
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批准号:19760286
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$1.41万
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财政年份:2007
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负责人:KANEKO Osamu
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依托单位:
Molecular basis of the intracellular trafficking of the malaria ligands
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批准号:19590428
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.91万
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财政年份:2007
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负责人:KANEKO Osamu
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依托单位:
Association of the Plasmodium falciparuminfected erythrocyte surface molecule with ist virulence
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批准号:17406009
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.38万
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财政年份:2005
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负责人:KANEKO Osamu
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依托单位:
Development of antisense technique for the malaria parasite
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批准号:17590372
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.3万
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财政年份:2005
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负责人:KANEKO Osamu
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依托单位:
海外基金