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Genetic manipulation to generate transgenic Plasmodium vivax invasive to the mature erythrocytes

Genetic manipulation to generate transgenic Plasmodium vivax invasive to the mature erythrocytes
基因操作产生侵入成熟红细胞的转基因间日疟原虫
批准号:
23659215
负责人:
KANEKO Osamu
金额:
$2.41万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012

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中文摘要
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英文摘要
In order to genetically modify Plasmodium vivax to invade into reticulocytes, I constructed artificial P. vivax chromosomes, from which a panel of Plasmodium falciparum erythrocyte ligands will be expressed under P. vivaxmerozoite-stage promoter. I also evaluated a transfection protocol to P. vivax obtained from infected patient in Thai field site.
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会议论文
Signaling mechanism of the apical organelle discharge by malaria parasites during erythrocyte invasion
  • 批准号:
    19H03461
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 资助金额:
    $11.15万
  • 财政年份:
    2019
  • 负责人:
    KANEKO Osamu
  • 依托单位:
Development of a live attenuated monkey malaria vaccine with enhanced antigenicity
  • 批准号:
    17K19566
  • 项目类别:
    Grant-in-Aid for Challenging Research (Exploratory)
  • 资助金额:
    $4.16万
  • 财政年份:
    2017
  • 负责人:
    KANEKO Osamu
  • 依托单位:
Signaling in malaria parasites during erythrocyte invasion
  • 批准号:
    16H05184
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 资助金额:
    $11.23万
  • 财政年份:
    2016
  • 负责人:
    KANEKO Osamu
  • 依托单位:
Molecular basis of the adaptation of Plasmodium knowlesi to human erythrocytes using mutator parasite lines
  • 批准号:
    15K15125
  • 项目类别:
    Grant-in-Aid for Challenging Exploratory Research
  • 资助金额:
    $2.41万
  • 财政年份:
    2015
  • 负责人:
    KANEKO Osamu
  • 依托单位:
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