Genetic manipulation to generate transgenic Plasmodium vivax invasive to the mature erythrocytes
Genetic manipulation to generate transgenic Plasmodium vivax invasive to the mature erythrocytes
批准号:
23659215
负责人:
KANEKO Osamu
金额:
$2.41万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012
中文摘要
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英文摘要
In order to genetically modify Plasmodium vivax to invade into reticulocytes, I constructed artificial P. vivax chromosomes, from which a panel of Plasmodium falciparum erythrocyte ligands will be expressed under P. vivaxmerozoite-stage promoter. I also evaluated a transfection protocol to P. vivax obtained from infected patient in Thai field site.
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会议论文
Signaling mechanism of the apical organelle discharge by malaria parasites during erythrocyte invasion
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批准号:19H03461
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.15万
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财政年份:2019
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负责人:KANEKO Osamu
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依托单位:
Development of a live attenuated monkey malaria vaccine with enhanced antigenicity
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批准号:17K19566
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项目类别:Grant-in-Aid for Challenging Research (Exploratory)
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资助金额:$4.16万
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财政年份:2017
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负责人:KANEKO Osamu
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依托单位:
Signaling in malaria parasites during erythrocyte invasion
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批准号:16H05184
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.23万
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财政年份:2016
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负责人:KANEKO Osamu
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依托单位:
Molecular basis of the adaptation of Plasmodium knowlesi to human erythrocytes using mutator parasite lines
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批准号:15K15125
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.41万
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财政年份:2015
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负责人:KANEKO Osamu
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依托单位:
Deciphering hypnozoite formation of Plasmodium vivax
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批准号:15H02656
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$26.96万
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财政年份:2015
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负责人:KANEKO Osamu
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依托单位:
Mechanism of the tropism switching of monkey malaria to human using Plasmodium knowlesi mutator line
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批准号:25670203
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.5万
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财政年份:2013
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负责人:KANEKO Osamu
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依托单位:
Signal transduction during erythrocyte invasion by malaria parasites
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批准号:25293102
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.15万
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财政年份:2013
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负责人:KANEKO Osamu
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依托单位:
Seroepidemiology of the molecules expressed on the Plasmodium vivax-infected erythrocyte surface
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批准号:24406012
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.32万
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财政年份:2012
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负责人:KANEKO Osamu
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依托单位:
Identification and targeting of the functional domains of malaria parasite's molecules involved in the erythrocyte invasion
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批准号:22390079
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.06万
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财政年份:2010
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负责人:KANEKO Osamu
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依托单位:
Design of data-driven lumped parameter canonical controller for distributed parameter system with its performance analysis
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批准号:22560442
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.66万
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财政年份:2010
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负责人:KANEKO Osamu
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依托单位:
Population genetics analysis of Plasmodium vivax-infected erythrocyte surface protein PvSTP
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批准号:20406009
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.9万
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财政年份:2008
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负责人:KANEKO Osamu
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依托单位:
On MPUM theory for dynamical systems defined by the rings : Kernel representation approach
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批准号:19760286
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$1.41万
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财政年份:2007
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负责人:KANEKO Osamu
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依托单位:
Molecular basis of the intracellular trafficking of the malaria ligands
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批准号:19590428
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.91万
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财政年份:2007
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负责人:KANEKO Osamu
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依托单位:
Association of the Plasmodium falciparuminfected erythrocyte surface molecule with ist virulence
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批准号:17406009
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.38万
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财政年份:2005
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负责人:KANEKO Osamu
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依托单位:
Development of antisense technique for the malaria parasite
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批准号:17590372
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.3万
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财政年份:2005
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负责人:KANEKO Osamu
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依托单位:
海外基金