Effects of exercise-induced interleukin-6 secretion on protein synthesis in skeletal muscle
Effects of exercise-induced interleukin-6 secretion on protein synthesis in skeletal muscle
批准号:
20500577
负责人:
NAKAI Naoya
金额:
$2.83万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
Murine myoblast cell line was mechanically stretched as a model for exercise-induced muscle contraction. Mechanical stretch increased the gene expression of interleukin-6 and activated the protein translation initiation. Stretch-induced activation of the protein translation initiation was completely blocked by tyrosin kinase inhibitor, genistein. Among the cellular protein which is activated by tyrosine kinase, phospholipase C was important for the signal transduction of mechanical stretch-induced activation of protein translation initiation.
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Myonucleus-related properties in soleus muscle fibers of mdx mice.
mdx 小鼠比目鱼肌纤维的肌核相关特性。
DOI:
--
发表时间:
2010
期刊:
Cell.Tissue.Organ.
影响因子:
--
作者:
[Terada M., et al.]
通讯作者:
et al.
Tyrosine phosphorylation regulates mechanical stretch-induced activation of protein translation initiation in C2C12 myoblast
酪氨酸磷酸化调节 C2C12 成肌细胞中机械拉伸诱导的蛋白质翻译起始激活
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Nakai, N., Kawano, F., Oke, Y., Nomura, S., Ohira, T., Fujita, R., Ohira, Y.]
通讯作者:
Y.
Mechanical stretch induces activation of eukaryotic elongation factor 2 in C2C12 myoblasts
机械拉伸诱导 C2C12 成肌细胞中真核伸长因子 2 的激活
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[N. Nakai, F. Kawano, Y. Oke, S. Nomura, M. Terada, T. Ohira, and Y, Ohira]
通讯作者:
Ohira
DOI:
10.1152/ajpcell.00497.2007
发表时间:
2008-08-01
期刊:
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
影响因子:
5.5
作者:
[Kawano, Fuminori, Takeno, Yoshiaki, Ohira, Yoshinobu]
通讯作者:
Ohira, Yoshinobu
Protein translation initiation is activated by mechanical stretch in C2C12 myoblast.
蛋白质翻译起始是由 C2C12 成肌细胞中的机械拉伸激活的。
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Nakai, N., Kawano, F., Oke, Y., Nomura, S., Terada, M., Ohira, T., Ohira, Y.]
通讯作者:
Y.
共 15 条
Skeletal muscle cell activation by atmospheric plasma exposure and application to tissues
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批准号:23650405
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.41万
-
财政年份:2011
-
负责人:NAKAI Naoya
-
依托单位:
Investigation of the role of branched chain amino add on stimulation of protein synthesis and application for preservation and improvement of muscle mass
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批准号:18500509
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.57万
-
财政年份:2006
-
负责人:NAKAI Naoya
-
依托单位:
海外基金