Development of Nano Device to Detect Cellular Stress by Using Supercritical Coating method.

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In this work, we synthesized the peptides including an amino benzoic acid group as fluorescent probe in supercritical carbon dioxide in order to detect ACE inhibitor which reduces hypertension. The cellular stress detection was tried by using this synthesized fluorescent peptide. The effect of ACE inhibitor on the reduction of the cellular stress and blood vessel dilation was experimentally examined by means of cardiomyocyte. Furthermore, in order to search the hypertension control substances, separation and purification of target substances included in the soybean milk and the tofu (food related to the soybean) were carried out by using the synthesized fluorescent peptide.