Research for structure and function of bacterial cation transport systems

细菌阳离子传输系统的结构与功能研究

• 批准号: 20570141
• 负责人: NAKAMURA Tatsunosuke
• 金额: $ 3.08万
• 依托单位: Nigata University of Phermacy and Applied Life Sciences
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2008
• 资助国家: 日本
• 起止时间: 2008 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20570141/
• 关键词: カチオン輸送; 交換輸送系; 膜タンパク質; 細胞内イオン調節; 細胞内pH調節; Na^+/H^+交換輸送系; NHE; NhaA; K^+/H^+交換輸送; NhaP2; 構造と機能; アンチポーター; 物質輸送; イオン輸送機構; 細胞生物学; エネルギー代謝; イオン輸送

What is the function of many membrane proteins written in the genome of Vibrio? Which is the gene that code K+/H+antiporter function for internal pH regulation in Vibrio? Does internal Ca^<2+> concentration be maintained low? If so, what kind of transporter does the task. What kind of real functions of Pha system, NhaP2, Fku, Trk and Ktr in Vibrio cells? We looked forward such queries and found some answers.

许多膜蛋白写在弧菌基因组中的功能是什么？哪个基因是颤音中内部pH调节的代码K+/H+抗管函数？内部Ca^<2+>浓度是否保持低含量？如果是这样，那么哪种运输者可以执行任务。 PHA系统，NHAP2，FKU，TRK和KTR在Vibrio细胞中的哪种实际功能？我们期待着这样的疑问，并找到了一些答案。

项目成果

The Implication of YggT of Escherichia coli in Osmotic Regulation

• DOI: 10.1271/bbb.90558
• 发表时间: 2009-12-01
• 期刊: BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
• 影响因子: 1.6
• 作者: Ito, Tomokazu;Uozumi, Nobuyuki;Yoshimura, Tohru
• 通讯作者: Yoshimura, Tohru

Glultamate 85 is involved in the sodium/proton exchange activity of the Escherichia coli ChaA

谷氨酸 85 参与大肠杆菌 ChaA 的钠/质子交换活性

• 发表时间: 2010
• 期刊: Biosci Biotechnol Biochem
• 作者: Fukaya F;Tanaka K;Waditee R;Tanaka Y;Nakamura T;Takabe T
• 通讯作者: Takabe T

Glutamate 85 is involved in the sodium/proton exchange activity of the Escherichia coli Cha A.

谷氨酸 85 参与大肠杆菌 Cha A 的钠/质子交换活性。

• 发表时间: 2010
• 期刊: Biosci.Biotechnol.Biochem.
• 作者: 平林佳;岩永朋子;高橋康弘;福山恵一;和田啓;Fukaya F
• 通讯作者: Fukaya F

pH-dependent regulation of the multi-subunit cation/proton antiporter Pha1 system from Sinorhizobium meliloti.

• DOI: 10.1099/mic.0.028563-0
• 发表时间: 2009-08
• 期刊: Microbiology
• 影响因子: 1.5
• 作者: Toshio Yamaguchi;F. Tsutsumi;P. Putnoky;M. Fukuhara;Tatsunosuke Nakamura

Function of lanI in regulation of landomycin A biosynthesis in Streptomyces cyanogenus S136 and cross-complementation studies with Streptomyces antibiotic regulatory proteins encoding genes

• DOI: 10.1007/s00203-007-0299-5
• 发表时间: 2008-02
• 期刊: Archives of Microbiology
• 影响因子: 2.8
• 作者: Y. Rebets;Lilia Dutko;B. Ostash;A. Luzhetskyy;Olexandr Kulachkovskyy;Toshio Yamaguchi;Tatsunosuke Nakamura;A. Bechthold;V. Fedorenko