Study on the functional mechanisms of androgens in differentiation of the mouse submandibular gland
Study on the functional mechanisms of androgens in differentiation of the mouse submandibular gland
批准号:
20590187
负责人:
ISEKI Shoichi
金额:
$3.0万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
点击翻译按钮获取中文摘要
英文摘要
The duct system of mouse submandibular gland has a pronounced sexual dimorphism, in which granular convoluted tubules (GCT) are developed preferentially in males, but its molecular mechanisms are unclear. The present study has revealed that JunD and CREB, which belong to the transcription factors functioning downstream of transmembrane receptors, disappear from the nuclei as a result of androgen-induced differentiation of GCT cells from striated duct cells. These results suggest that a special kind of cross-talk between the androgen receptor and other transcription factors is involved in the differentiation of the submandibular duct system.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
The duct system of mouse submandibular gland : a model of hormone-dependent cell differentiation..
小鼠颌下腺导管系统:激素依赖性细胞分化模型。
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[中舘和彦, 大桃秀樹, 江原鮎香, 榊原伸一, 上田秀一, 井関尚一]
通讯作者:
井関尚一
The role of cyclic AMP response element-binding protein in the duct cell differentiation in mouse submandibular gland
环AMP反应元件结合蛋白在小鼠颌下腺导管细胞分化中的作用
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Iseki S, Keattikunpairoj S, Sakulsak N, Nakaya M-A, Wakavama T]
通讯作者:
Wakavama T
マウス顎下腺における受容体型蛋白質チロシンフォスファターゼの発現と局在
受体型蛋白酪氨酸磷酸酶在小鼠颌下腺中的表达及定位
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[井関尚一, Keattikunpairoj S, Phanmatchaya K, 若山友彦, 山本美由紀, 仲田浩規]
通讯作者:
仲田浩規
The duct system of mouse submandibular gland a model of hormone-dependent cell differentiation
小鼠颌下腺导管系统激素依赖性细胞分化模型
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Kiyama H., Shishioh-Ikejima N., Ogawa T., 榊原伸一, Iseki S]
通讯作者:
Iseki S
マウス顎下腺導管系の分化における転写因子CREBの発現と盾性化
小鼠颌下腺导管系统分化过程中转录因子CREB的表达及屏蔽
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Keatthikunpairoji S, 井関尚一]
通讯作者:
井関尚一
共 17 条
Molecular mechanisms in the hormone-dependent differentiation of the mouse submandibular gland
-
批准号:26460270
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.24万
-
财政年份:2014
-
负责人:ISEKI Shoichi
-
依托单位:
Roles of the androgen receptor in the sexual differentiation in the mouse submandibular gland
-
批准号:23590231
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.41万
-
财政年份:2011
-
负责人:ISEKI Shoichi
-
依托单位:
GENE EXPRESSION DURING THE DUCT CELL DIFFERENTIATION IN SALIVARY GLANDS
-
批准号:17590154
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.3万
-
财政年份:2005
-
负责人:ISEKI Shoichi
-
依托单位:
The mechanism of androgen-dependent differentiation of the duct system in the submandibular gland
-
批准号:15590156
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.3万
-
财政年份:2003
-
负责人:ISEKI Shoichi
-
依托单位:
The signal-transduction mechanisms of the cell proliferation and differentiation in the submandibular gland
-
批准号:13670006
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.62万
-
财政年份:2001
-
负责人:ISEKI Shoichi
-
依托单位:
Expression and localization of vascular endothelial growth factor in the endocrine system
-
批准号:09670006
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.05万
-
财政年份:1997
-
负责人:ISEKI Shoichi
-
依托单位:
A histochemical study on the expression and localization of growth factors
-
批准号:06670014
-
项目类别:Grant-in-Aid for General Scientific Research (C)
-
资助金额:$1.34万
-
财政年份:1994
-
负责人:ISEKI Shoichi
-
依托单位:
Expression and localization of intestine-derived faty acid-binding proteins in the rat
-
批准号:04670009
-
项目类别:Grant-in-Aid for General Scientific Research (C)
-
资助金额:$1.28万
-
财政年份:1992
-
负责人:ISEKI Shoichi
-
依托单位:
Immunohistochemical Study on the Occurrence, Morphology and Development of the Gastrointestinal Brush Cells of the Rat
-
批准号:01570006
-
项目类别:Grant-in-Aid for General Scientific Research (C)
-
资助金额:$1.34万
-
财政年份:1989
-
负责人:ISEKI Shoichi
-
依托单位:
海外基金