Roles of the PrRP-oxytocin pathway in the control of stress and social behaviour

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Not only stressful stimuli but also food intake activated PrRP-synthesizing neurons and oxytocin-synthesizing neurons. Social stimuli activated oxytocin-synthesizing neurons. PrRP-synthesizing neurons were suggested to have stress-modulating and anorexic actions. Oxytocin-synthesizing neurons were suggested to have anti-stress, anorexic and social memory-enhancing actions. Downstream neurons of oxytocin-synthesizing neurons were suggested to be serotoninergic.