Analyze the mechanism of onset of Graves' disease, using high sensitivity method for TSH receptor antibody

点击翻译按钮获取中文摘要

The peripheral blood mononuclear cells (PBMC) from the Graves' patients complicated with cedar pollen allergy were stimulated with cedar pollen. TSH receptor antibody (TRAb) could be detected in the supernatant using high sensitivity method. However, TRAb also could be detected in the supernatant incubated without the stimulation of cedar pollen. Moreover, TRAb could be detected in the supernatant incubated PBMC from the Graves' patients without cedar pollen allergy. Therefore, we could not demonstrate that the cedar pollen stimulates the production of TRAb.