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Evolution of the body temperature regulation mechanisms in homeothermic animals : Comparative analysis of the genes related to thermoperception and nonshivering thermogenesis

Evolution of the body temperature regulation mechanisms in homeothermic animals : Comparative analysis of the genes related to thermoperception and nonshivering thermogenesis
恒温动物体温调节机制的进化:与温度感知和非颤抖产热相关的基因的比较分析
批准号:
20770191
负责人:
SAITO Shigeru
金额:
$2.83万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010

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中文摘要
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英文摘要
1) Placental mammals maintain body temperature by nonshivering thermogenesis in cold environments, and uncoupling protein 1 (UCP1) and β3 adrenoceptor play crucial roles. Investigating the evolutionary process of these two genes revealed that the evolutionary origins were much earlier than the emergence of placental mammals. In addition, the tissue distribution of UCP1 in western clawed frog (ectotherm) was different from that of placental mammals. 2) TRPV3, which serves as a warm temperature receptor in mammals, was cloned from western clawed frog and its property was examined. TRPV3 of western clawed frog perceives cold temperature, suggesting that temperature sensitivities of TRPV3 have changed in the course of vertebrate evolution.
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会议论文
温度と生命システムの相関学(第4章)動物における温度センサーの進化
温度与生命系统的相关性(第四章)动物温度传感器的进化
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [齋藤茂, 新貝鉚蔵]
通讯作者: 新貝鉚蔵
温度と生命システムの相関学、第4章 動物における温度センサーの進化
温度与生命系统之间的相关性,第 4 章:动物温度传感器的进化
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [齋藤茂, 新貝鉚蔵, 齋藤茂]
通讯作者: 齋藤茂
DOI: --
发表时间:
期刊:
影响因子: --
作者: []
通讯作者:
熱産生における脱共役タンパク質の役割と適応進化
解偶联蛋白在产热和适应性进化中的作用
DOI: --
发表时间: 2008
期刊: 化学と生物 46巻
影响因子: --
作者: [稲葉(伊東)靖子, 齋藤茂]
通讯作者: 齋藤茂
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