Bidirectional approach with neurotrophic factors for the acceleration of neuro-regeneration.
Bidirectional approach with neurotrophic factors for the acceleration of neuro-regeneration.
批准号:
20390411
负责人:
SAITO Shigeru
金额:
$7.49万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
For the better recovery of damaged neurons, cellular environment seems to be crucial. In the present study, the authors assessed effects of neurotrophic factors in various settings. As the results, it was revealed that normo-glycemia is the best condition for the neuro-regeneration. Newly developed drug delivery system was identified as effective for gradual release of nerve activity controlling drugs.
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Thermal hyperalgeria via supraspinal mechanisms in mice lacking glutamate decarboxylase 65
缺乏谷氨酸脱羧酶的小鼠通过脊髓上机制引起热过敏65
DOI:
--
发表时间:
2009
期刊:
J Pharmacol Exp Ther Vol.331(1)
影响因子:
--
作者:
[Kubo K, Nishikawa K, Hardy-Yamada M, Ishizeki J, Yanagawa Y, Saito S, Kubo K]
通讯作者:
Kubo K
Anatomic analysis of computed tomography images obtained during fluoroscopic computed tomography-guided percutaneous lumbar symnathectomy.
对荧光计算机断层扫描引导经皮腰椎交感神经切除术期间获得的计算机断层扫描图像进行解剖分析。
DOI:
--
发表时间:
2008
期刊:
Journal of Anesthesia 22
影响因子:
--
作者:
[Koizuka S, Saito S, Obata H, robe M, Koyama Y, Takahashi A.]
通讯作者:
Takahashi A.
Monoamine-dependent, opioid-independent antihypersensitivity effects of intrathecally administered milnacipran, a serotonin noradrenaline reuptake inhibitor, in a postonerative pain model in rats.
鞘内注射米那普仑(一种血清素去甲肾上腺素再摄取抑制剂)在大鼠术后疼痛模型中的单胺依赖性、阿片类非依赖性抗过敏作用。
DOI:
--
发表时间:
2010
期刊:
J Pharmacol Exp Ther.
影响因子:
--
作者:
[南野勝彦, 名井陽, 杉安謙仁朗, 玉井宣行, 橋本伸之, 吉川秀樹, Obata H]
通讯作者:
Obata H
DOI:
10.1124/jpet.110.168336
发表时间:
2010-09-01
期刊:
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
影响因子:
3.5
作者:
[Obata, Hideaki, Kimura, Masafumi, Saito, Shigeru]
通讯作者:
Saito, Shigeru
DOI:
10.1080/09553000903020032
发表时间:
2009-01-01
期刊:
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
影响因子:
2.6
作者:
[Al-Jahdari,Wael S., Suzuki,Yoshiyuki, Nakano,Takashi]
通讯作者:
Nakano,Takashi
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