Studies of the pi3-kinase enzyme family using selective inhibitors

使用选择性抑制剂研究 pi3 激酶家族

• 批准号: LP0347992
• 负责人: Prof Philip Thompson
• 金额: $ 6.49万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2003
• 资助国家: 澳大利亚
• 起止时间: 2003-03-31 至 2008-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LP0347992
• 关键词: Studies; pi3; kinase; enzyme; family

The objective of this project is to study the function of the PI3-kinase enzyme family in blood platelets. To do this, inhibitors which block the action of specific family members, will be evaluated for their effects in assays of platelet function. The results will enhance our understanding of the way in which platelets and other cells respond to stimuli, and lead new approaches to designing novel drugs that block these responses.

本项目的目的是研究PI3-激酶家族在血小板中的功能。为了做到这一点，将评估阻断特定家族成员作用的抑制剂在血小板功能检测中的效果。这一结果将加深我们对血小板和其他细胞对刺激的反应方式的理解，并引领设计阻止这些反应的新药的新方法。