The basic study about kidney differentiation from gene transferred embryonic stem cells
The basic study about kidney differentiation from gene transferred embryonic stem cells
批准号:
20791119
负责人:
NAKANE Akihiro
金额:
$2.66万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2009
中文摘要
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英文摘要
By establishing tetracycline-inducible overexpression in ES cells, our data suggest that Pax2 and additional factors that are induced in the embryoid bodies synergistically upregulate the integrin α 8 and AQP1 that are possibly involved in kidney development. Our method for the generation of tetracycline-inducible ES cell lines will be useful for dissecting the genetic cascades functioning in the early stages of development, as well as for screening candidate genes that direct ES cells toward the desired lineages, which may be applicable to future cell therapies.
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Achieving a natural glanular meatus for distal hypospadias with a narrow and shallow plate: Tubularized incised plate versus modified Barcat repair.
用窄而浅的板实现远端尿道下裂的自然龟头鼻道:管状切割板与改良的 Barcat 修复术。
DOI:
--
发表时间:
2008
期刊:
International Journal of Urology 15
影响因子:
--
作者:
[Hayashi Y, Kojima Y, Mizuno K, Kurokawa S, Nakane A, Kohri K]
通讯作者:
Kohri K
Pax2遺伝子導入ES細胞からの尿細管細胞分化の基礎研究
Pax2基因转染ES细胞向肾小管细胞分化的基础研究
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[中根明宏, 林祐太郎, 黒川覚史, 水野 健太郎, 小島祥敬, 丸山哲史, 郡健二郎]
通讯作者:
郡健二郎
膀胱尿管逆流症における排尿状態の検討
膀胱输尿管反流病的泌尿状况检查
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[中根明宏, 林祐太郎, 丸山哲 史, 水野健太郎, 小島祥敬, 黒川覚史, 井村誠, 郡健二郎]
通讯作者:
郡健二郎
尿道下裂術後の排尿状態、外観、性機能に関する満足度のアンケート調査
尿道下裂术后排尿状况、外观及性功能满意度问卷调查
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[中根明宏, 林祐太郎, 水野健太郎, 小島祥敬, 丸山哲史, 郡健二郎]
通讯作者:
郡健二郎
Pax2 overexpression in embryoid bodies induces upregulation of integr in alpha8 and aquaporin-1.
Pax2 在拟胚体中的过表达会诱导 alpha8 和 aquaporin-1 中整合素的上调。
DOI:
--
发表时间:
2009
期刊:
In Vitro Cell Dev. Biol. Anim. 45(1-2)
影响因子:
--
作者:
[飯野則昭, 斎藤亮彦, 下条文武, Nakane A.]
通讯作者:
Nakane A.
共 12 条
The investigation of the mechanism about the kidney generation using embryonic stem cells with inducible gene expression by assesment of FACS, and the application to kidney regeneration medicine
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批准号:24592436
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.41万
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财政年份:2012
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负责人:NAKANE Akihiro
-
依托单位:
The basic research about the investigation of the mechanism about the kidney generation and the application to kidney regeneration medicine using Pax2-recombinant embryonic stem cells.
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批准号:22791485
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.58万
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财政年份:2010
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负责人:NAKANE Akihiro
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依托单位:
海外基金