Biogenesis of ion transporters and analysis of their functionalregulation
Biogenesis of ion transporters and analysis of their functionalregulation
批准号:
20710161
负责人:
SATO Yoko
金额:
$2.83万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2009
中文摘要
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英文摘要
The voltage sensors in voltage-dependent potassium channels (Kv channels) consist of the highly positively charged segment, S4, and the negatively charged segments, S2 and S3. How can such highly charged protein domains be efficiently inserted into biological membranes? In this study, we used in vitro translation and translocation experiments to evaluate interactions between residues in the voltage sensor of an archaeal potassium channel, KvAP, and their effect on the final topology in the endoplasmic reticulum (ER) membrane. These results suggest that insertion mechanism of the KvAP is different from plant and insect Kv channels.
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K^+チャネル膜電位センサーのトポロジー形成機構の解明
K^+通道膜电位传感器拓扑形成机制的阐明
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[三島枝里子, 佐藤陽子, 張麗艶, 阪口雅郎, 三島枝里子]
通讯作者:
三島枝里子
魚住信之K+チャネル膜電位センサーのトポロジー形成機構の解明
鱼住伸行阐明K+通道膜电位传感器的拓扑形成机制
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[三島枝里子, 佐藤陽子, 張麗艶, 阪口雅郎]
通讯作者:
阪口雅郎
魚住信之K+チャネル膜電位センサーの形成機構の解明
鱼住伸行阐明K+通道膜电位传感器的形成机制
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[佐藤陽子, 三島枝里子, 張麗艶, 阪口雅郎]
通讯作者:
阪口雅郎
イオン輸送系のトポロジー形成および活性調節
离子传输系统的拓扑形成和活性调节
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[佐藤陽子, 三島枝里子, 張麗艶, 阪口雅郎, 佐藤陽子, 三島枝里子, 佐藤陽子]
通讯作者:
佐藤陽子
K^+チャネル膜電位センサーの形成機構の解明
K^+通道膜电位传感器形成机制的阐明
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[佐藤陽子, 三島枝里子, 張麗艶, 阪口雅郎, 佐藤陽子]
通讯作者:
佐藤陽子
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Terminal Care and Criminal Law
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School-based social skills training to improve social adjustment of children with learning disabilities
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