Roles and possible treatment of lipoproteins in diabetic retinopathy

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The aims of this study are to analyze mechanisms of development of diabetic retinopathy and to develop novel treatments for this disorder. Diabetic retinopathy is one of the major complications in diabetes and induces dysfunction of retinal ganglion cells (RGCs). Thus, RGCs in cultures were led injury, analyzed the mechanisms of neuronal death and determined whether lipoproteins protect neurons. This study showed the mechanism of neuroprotection via the receptor of lipoproteins.