Efficient chicken meat production using orexigenic, antistress, and antiobesity peptides

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Central administration ofα-MSH antagonist did not influenced food intake in broiler chicks, suggesting that endogenousα-MSH is decreased in the hypothalamus of broiler chicks. Central administration of CRF antagonist decreased plasma corticosterone and increased food intake in broiler chicks, suggesting that CRF antagonist acts as an orexigenic, antistress, and antiobesity peptide. However, these effects of CRF antagonist were observed in layer chicks, but not in broiler chicks, when the peptide administered intranasally. It is therefore likely that the rate of transportation of peptides from the nasal cavity to the central nervous system in broiler chicks is lower than that in layer chicks.