Long-term prognosis and management of clinically ill infants :"Fetal origin of adult disease" hypothesis
Long-term prognosis and management of clinically ill infants :"Fetal origin of adult disease" hypothesis
批准号:
21591314
负责人:
TSUKAHARA Hirokazu
金额:
$2.91万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
我们已经在新生儿、婴儿和儿童中建立了几种氧化应激标志物,如NOx、ADMA和8-OHdG。这些参数的测量使我们能够无创和顺序地评估各种疾病儿童的NO-ADMA系统和氧化环境。8-OHdG测量的快速测试也可用。在临床领域使用这些方法的进一步研究正在进行中。
英文摘要
We have established several oxidative stress markers such as NOx, ADMA, and 8-OHdG in neonates, infants, and children. Measurement of these parameters enables us to evaluate NO-ADMA system and oxidative environment non-invasively and sequentially in children with various disorders. Rapid test for 8-OHdG measurement is also available. Further studies using these procedures are in progress in the clinical field.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
ありふれた臨床検査から読めること・考えられること
您可以从常见的临床测试中学到什么和思考什么
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[遠藤真美子, 藤井克則, 水落弘美, 須山麻衣子, 内川英紀, 宮下俊之, 斎藤加代子, 杉田克生, 河野陽一, Kobayashi R,, 塚原宏一]
通讯作者:
塚原宏一
DOI:
10.1016/j.metabol.2010.08.008
发表时间:
2011-06-01
期刊:
METABOLISM-CLINICAL AND EXPERIMENTAL
影响因子:
9.8
作者:
[Nagasaka, Hironori, Yorifuji, Tohru, Miida, Takashi]
通讯作者:
Miida, Takashi
Altered metabolisms of mediators controlling vascular function and enhanced oxidative stress in asymptomatic children with congenital portosystemic venous shunt.
先天性门体静脉分流的无症状儿童控制血管功能的介质代谢发生改变,氧化应激增强。
DOI:
--
发表时间:
2010
期刊:
Metabolism Vol.59,No.1
影响因子:
--
作者:
[Nagasaka H, Okano Y, Aizawa M, Miida T, Yorifuji T, Tajima, G Sakura N, Takatani T, Sanayama Y, Sugamoto K, Mayumi M, Kobayashi K, Hirano K, Takayanagi M, Tsukahara H]
通讯作者:
Tsukahara H
Cross-sectional study of bone metabolism along with nutrition in adult classical phenylketonuric patients diagnosed byneonatal screening
新生儿筛查诊断的成人经典苯丙酮尿症患者骨代谢与营养的横断面研究
DOI:
--
发表时间:
2011
期刊:
J Bone Miner Metab
影响因子:
3.3
作者:
[Nagasaka H, Tsukahara H, Takatani T, Sanayama Y, Takayanagi M, Ohura T, Sakamoto O, Ito T, Wada M, Yoshino M, Ohtake A, Yorifuji T, Hirayama S, Miida T, Fujimoto H, Mochizuki H, Hattori T, Okano Y]
通讯作者:
Okano Y
酸化ストレスの生体マーカー-最近の進歩
氧化应激的生物标志物——最新进展
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[小橋吉博, 宮下修行, 塚原宏一]
通讯作者:
塚原宏一
共 29 条
Stress response evaluation and novel therapy development in advanced cardiac and pulmonary diseases in children
-
批准号:16K10067
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.83万
-
财政年份:2016
-
负责人:TSUKAHARA Hirokazu
-
依托单位:
Integrative study on the biological response modifications by arginine-related molecules including NO and ADMA
-
批准号:19591201
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.91万
-
财政年份:2007
-
负责人:TSUKAHARA Hirokazu
-
依托单位:
Elucidation of molecular mechanisms and therapeutic strategies for diabetic angiopathic complications
-
批准号:17591074
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.37万
-
财政年份:2005
-
负责人:TSUKAHARA Hirokazu
-
依托单位:
Therapeutic strategies of redox modification for renal failure
-
批准号:13670789
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.92万
-
财政年份:2001
-
负责人:TSUKAHARA Hirokazu
-
依托单位:
Microvascular endothelial control of bone metabolism in rats: nitric oxide and endothelin systems
-
批准号:10670713
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.66万
-
财政年份:1998
-
负责人:TSUKAHARA Hirokazu
-
依托单位:
海外基金