Comprehensive analysis for genomic contribution in neuron network and transcripts

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This study was aimed to clarify the abnormal genome copy number in patients with developmental disorders in children. The impact of the abnormal genomic copy number for the neurological symptoms was investigated. We identified novel genomic copy number aberrations in pediatric patients with neurological disease. In order to identify the genes that were included in the relevant area and affect the development of the central nervous system, we analyzed the expression patterns of the genes in patient-derived cells.