Significance of serum bile acid level to predict the effective functional hypertrophy of the nonembolized liver after portal vein embolization

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The clinical association between serum bile acid level changes and liver hypertrophy in portal vein embolization(PVE) is unknown. We clarified that PVE increases the serum bile acid level in patients with effective liver hypertrophy and the increase on day 3 is a useful predictor of effective hypertrophy(r=0. 613、P=0. 002). Serum bile acid levels were significantly higher in non-external bile drainage group and the regenerated liver volume was significantly greater(129ml vs. 39ml, P<0. 05). Besides, serum bile acid level is a useful predictor of liver regeneration.