The development of the new therapy by kinetic analysis and the redox adjustment of the oxidative stress in cerebrovascular disorder.
The development of the new therapy by kinetic analysis and the redox adjustment of the oxidative stress in cerebrovascular disorder.
批准号:
21591856
负责人:
YOSHIDA Kenji
金额:
$2.83万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
我们分析了脑缺血/再灌注在缺血性脑血管病中的作用及外科治疗,明确了再通后的过度灌注与脑缺血的程度有关。术后认知功能的改善确实与大脑皮层神经细胞苯二氮卓类受体功能的改善有关。此外,我们还首次报道了这些现象是可逆的变化。我们建立了一种新的脑代谢SPECT检查技术,可以在不使用常见的副作用药物的情况下进行评估。
英文摘要
We analyzed the effect that cerebral ischaemia/reperfusion in ischemic cerebrovascular disease and the surgical treatment, made clear that hyperperfusion after the recanalization correlated with degree of cerebral ischaemia. The improvement of a postoperative cognitive function did that we correlated with improvement the benzodiazepine receptor function of the brain cortex nerve cells. Also, we reported the first time that these phenomenon were reversible changes. We established the new examination technique of the SPECT for cerebral metabolism that could evaluate without use the frequent medicine of the side effect.
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脳血管反応性測定のためのアセトゾラマイド投与による副作用の検討ton MRSを用いた非侵略的脳温測定による慢性脳虚血における脳循環代謝の評価:PETとの比較
检查用于测量脑血管反应性的乙酰唑胺给药的副作用 Ton 通过 MRS 无创脑温度测量评估慢性脑缺血的脑循环和代谢:与 PET 的比较
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Bito Y, Hirata K, Ebisu T, Kawai Y, Otake Y, Hirata S, Shirai T, Soutome Y, Ochi H, Umeda M, Higuchi T, Tanaka C, 斎藤秀夫]
通讯作者:
斎藤秀夫
Iomazenil SPECTを用いた貧困灌流擬似画像:第四報:頚動脈内膜剥離術後の合併症の出現予知への応用
使用 Iomazenil SPECT 的不良灌注伪图像:第四份报告:在预测颈动脉内膜切除术后并发症中的应用
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[村瀬智一, 河合裕子, 渡邉康晴, 梅田雅宏, 樋口敏宏, 田中忠蔵, 小笠原邦昭]
通讯作者:
小笠原邦昭
DOI:
10.2176/nmc.52.154
发表时间:
2012-03-01
期刊:
NEUROLOGIA MEDICO-CHIRURGICA
影响因子:
1.9
作者:
[Yoshida, Koji, Ogasawara, Kuniaki, Ogawa, Akira]
通讯作者:
Ogawa, Akira
DOI:
10.1179/174313209x382269
发表时间:
2009-09-01
期刊:
NEUROLOGICAL RESEARCH
影响因子:
1.9
作者:
[Kobayashi, Masakazu, Ogasawara, Kuniaki, Ogawa, Akira]
通讯作者:
Ogawa, Akira
Scar formation in the carotid sheath identified during carotid endarterectomy in patients with previous cardiac surgery : significance of history of intraoperative Swan-Ganz catheter insertion. Clinical article.
既往心脏手术患者颈动脉内膜切除术期间颈动脉鞘中形成的疤痕:术中 Swan-Ganz 导管插入史的意义。
DOI:
--
发表时间:
2010
期刊:
J Neurosurg. 113(4)
影响因子:
--
作者:
[Yoshida K, Ogasawara K, Kobayashi M, Tsuboi J, Okabayashi H, Ogawa A]
通讯作者:
Ogawa A
共 52 条
Cross-linguistic study on articulatory coordination in speech production
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批准号:17K02692
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.25万
-
财政年份:2017
-
负责人:YOSHIDA Kenji
-
依托单位:
Skill analysis of urological robotic surgery and development of new educational method
-
批准号:16K20167
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项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.66万
-
财政年份:2016
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负责人:YOSHIDA Kenji
-
依托单位:
Platform for Integration and Sophistication of Image Information on Area Studies
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批准号:16H06281
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项目类别:Grant-in-Aid for Scientific Research on Innovative Areas ― Platforms for Advanced Technologies and Research Resources
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资助金额:$49.92万
-
财政年份:2016
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负责人:YOSHIDA Kenji
-
依托单位:
Evaluation on specific adsorption of targeted microbubbles using a piezoelectric resonator
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批准号:25870901
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项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.75万
-
财政年份:2013
-
负责人:YOSHIDA Kenji
-
依托单位:
The study of oral cancer screening by photo imaging
-
批准号:24593019
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.24万
-
财政年份:2012
-
负责人:YOSHIDA Kenji
-
依托单位:
Study for the Impact of Nuclear Factor-κB Expression in the radiosresitant Tumors
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批准号:23791426
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.58万
-
财政年份:2011
-
负责人:YOSHIDA Kenji
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依托单位:
Investigation on biosensor using interaction between ultrasound and microbubble
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批准号:22700517
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项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.58万
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财政年份:2010
-
负责人:YOSHIDA Kenji
-
依托单位:
Reconstructing the History of Africa through Material Culture
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批准号:21242034
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项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$29.29万
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财政年份:2009
-
负责人:YOSHIDA Kenji
-
依托单位:
Study on the Muromachi Bakufu's System
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批准号:20720172
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$1.08万
-
财政年份:2008
-
负责人:YOSHIDA Kenji
-
依托单位:
Research on the transcriptional mechanism of the smooth muscle cell under the vasospasm following subarachnoid hemorrhage
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批准号:18591602
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.34万
-
财政年份:2006
-
负责人:YOSHIDA Kenji
-
依托单位:
Study of Indirect Detection of Dark Matter by Cosmic-Ray Electron and Positron Observations
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批准号:18540293
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.46万
-
财政年份:2006
-
负责人:YOSHIDA Kenji
-
依托单位:
Search for high-energy electron sources with Polar Patrol Balloon
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批准号:16540268
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.11万
-
财政年份:2004
-
负责人:YOSHIDA Kenji
-
依托单位:
Tracing the Histories of Bantu Civilization through Material Culture : A Museological Approach
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批准号:14251011
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项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$21.63万
-
财政年份:2002
-
负责人:YOSHIDA Kenji
-
依托单位:
The investigation of mechanisms between PDT and metastatic effect of oral cancer
-
批准号:11672026
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.54万
-
财政年份:1999
-
负责人:YOSHIDA Kenji
-
依托单位:
Ethnicity and Cultural Movements in Africa
-
批准号:10041055
-
项目类别:Grant-in-Aid for Scientific Research (A).
-
资助金额:$18.5万
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财政年份:1998
-
负责人:YOSHIDA Kenji
-
依托单位:
Reconsidering "Modernity" from an Ethnological Point of View : An Analysis of Ethnographic Photo-Archives
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批准号:07044019
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项目类别:Grant-in-Aid for international Scientific Research
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资助金额:$17.92万
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财政年份:1995
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负责人:YOSHIDA Kenji
-
依托单位:
Effect of low power laser irradiation on cultured fibroblast cells.
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批准号:07672200
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.47万
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财政年份:1995
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负责人:YOSHIDA Kenji
-
依托单位:
Measurement of the distance to gamma-ray burst surces
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批准号:06640356
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.34万
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财政年份:1994
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负责人:YOSHIDA Kenji
-
依托单位:
Study to clarify the tissue acceleration of low power output laser irradiation
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批准号:05807192
-
项目类别:Grant-in-Aid for General Scientific Research (C)
-
资助金额:$1.15万
-
财政年份:1993
-
负责人:YOSHIDA Kenji
-
依托单位:
海外基金