Analysis of lethal pathogenicity mechanism of herpesvirus in non-natural host
Analysis of lethal pathogenicity mechanism of herpesvirus in non-natural host
批准号:
21380179
负责人:
FUKUSHI Hideto
金额:
$12.4万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
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英文摘要
The object of this research is to reveal the molecular mechanism of herpesvirus lethal encephalitis in non-natural host. Equine herpesviruses(EHVs) 1 and 9 were used. Virus genes involving in the lethal encephalitis in non-natural host were identified. Comparison of neuropathogenic and non-neuropathogenic EHV-1s showed nine gene differences between their whole genome sequences. Comprehensive transcriptome analysis in EHV-infected cells were examined. Several viral and host genes were identified as variable transcript encoded genes in EHV-infected cells.
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Equine Herpesvirus 9(EHV-9)-induced encephalitis in non-human primates.In "Non-flavivirus Encephalitis" ed.Sergey Tkachev, pp.147-156
马疱疹病毒 9 (EHV-9) 诱发的非人灵长类脑炎。In“非黄病毒脑炎”编辑 Sergey Tkachev,第 147-156 页
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Yanai, T., Kodama, A., Sakai, H., Fukushi, H., Hattori, S., Kai, C.]
通讯作者:
C.
The effect of point mutation found in Equine Herpesvirus BAC clone, Ab4p attB, to the pathogenicity in the hamster model
马疱疹病毒 BAC 克隆 Ab4p attB 点突变对仓鼠模型致病性的影响
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[郭小芹,岡田彩加, Abdelaziz Amira,大屋賢司,福士秀人]
通讯作者:
Abdelaziz Amira,大屋賢司,福士秀人
DOI:
10.1016/j.virol.2010.02.012
发表时间:
2010-05-10
期刊:
VIROLOGY
影响因子:
3.7
作者:
[Kasem, Samy, Yu, Mi Htay Htay, Fukushi, Hideto]
通讯作者:
Fukushi, Hideto
ウマヘルペスウイルス1型テグメントタンパクVP22の細胞内動態解析
马疱疹病毒1型皮膜蛋白VP22的细胞内动力学分析
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Iwanaga, K., Murata, T, Hori M, Ozaki H, 岡田彩加,羽入さち子,大屋賢司,福士秀人]
通讯作者:
岡田彩加,羽入さち子,大屋賢司,福士秀人
ウマヘルペスウイルス増殖に優れたウマ胎仔脳由来細胞株の樹立
马疱疹病毒生长良好的马胎脑源细胞系的建立
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[岡田彩加, Samy Kasem,辻村行司,松村富夫,大屋賢司,福士秀人]
通讯作者:
Samy Kasem,辻村行司,松村富夫,大屋賢司,福士秀人
共 20 条
Studies on the function of the long noncoding region in herpesvirus replication
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批准号:26660228
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项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.5万
-
财政年份:2014
-
负责人:FUKUSHI Hideto
-
依托单位:
Studies on novel gene expression regulation system by anti-sense RNA in herpesvirus multiplication
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批准号:24658256
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.58万
-
财政年份:2012
-
负责人:FUKUSHI Hideto
-
依托单位:
Studies on neuropathogenesis of equine herpesviruses
-
批准号:24380165
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.82万
-
财政年份:2012
-
负责人:FUKUSHI Hideto
-
依托单位:
Survey for lethal zoonoses and potential emerging and re-emerging infectious diseases in Africa
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批准号:17255010
-
项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$26.29万
-
财政年份:2005
-
负责人:FUKUSHI Hideto
-
依托单位:
Pathogenic proteomics on the expression of pathogenesis of the new lethal neuropathogenic herpesvirus
-
批准号:17380181
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$10.89万
-
财政年份:2005
-
负责人:FUKUSHI Hideto
-
依托单位:
Molecular pathobiological study on neuropathogenicity of a new lethal neurotropic herpesvirus
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批准号:14560264
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.3万
-
财政年份:2002
-
负责人:FUKUSHI Hideto
-
依托单位:
Molecular pathogenic study on neuropathogenicity of a new lethal and neurotropic herpesvirus
-
批准号:12660283
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.3万
-
财政年份:2000
-
负责人:FUKUSHI Hideto
-
依托单位:
Pathogenicity and molecular structer of a newly isolated lethal and broad host range herpesvirus
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批准号:10660299
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.3万
-
财政年份:1998
-
负责人:FUKUSHI Hideto
-
依托单位:
DEVELOPEMENT OF ASSAY SYSTEMS FOR EARLY DIAGNOSIS AND DETECTION OF CHLAMYDIAL INFECTIONS
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批准号:07556120
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项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$4.22万
-
财政年份:1995
-
负责人:FUKUSHI Hideto
-
依托单位:
Molecular biological analysis of pathogenesis of Chlamydia psittaci
-
批准号:05660342
-
项目类别:Grant-in-Aid for General Scientific Research (C)
-
资助金额:$1.41万
-
财政年份:1993
-
负责人:FUKUSHI Hideto
-
依托单位:
海外基金