Investigation of benthonic marine organisms in Indonesia searching for new medicinal seeds.
Investigation of benthonic marine organisms in Indonesia searching for new medicinal seeds.
批准号:
21406002
负责人:
KOBAYASHI Motomasa
金额:
$10.9万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
为了开发新的药用资源,我们在印度尼西亚帝汶岛西侧(Kupang地区)、Biak岛周围和Flores岛(Maumere地区)的珊瑚礁中采集了279份底栖海洋生物标本,并对标本进行了制备和提取。此外,我们还根据水下海洋生物的照片、生物测定结果和样品中的有效成分,编制了包含分布、环境和形态特征信息的样品清单。我们还编制了从海沙和海洋生物中分离的140种真菌的清单。
英文摘要
To develop the new medicinal resources, we collected 279 samples of benthonic marine organisms in the coral reef of the west side of Timor Island(Kupang area), the around of Biak Island and the Flores Island(Maumere area) at Indonesia, and prepared the specimen and the extracts from the collected samples. In addition, we prepared the list of samples, which contained information of the distribution, environments and morphological characteristics based on the pictures of marine organisms under the water, results of the bioassay and the active constituents in the samples. We also have prepared the list of 140 kinds of fungi isolated from sea sands and marine organisms.
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インドネシア産海綿由来の新規環状ペプチドaxinellin Dのがん細胞浸潤阻害作用
印度尼西亚海绵新型环肽axinellin D的癌细胞侵袭抑制作用
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[山野喜, 荒井雅吉, 藤田真由美, 小林資正]
通讯作者:
小林資正
海洋生物成分からの新しい抗がん剤シーズ探索
从海洋生物成分中寻找新的抗癌药物种子
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[荒井雅吉, 古徳直之, 小林資正]
通讯作者:
小林資正
海洋由来真菌が産生する5-methoxysterigmatocystinのbiofilm形成阻害活性
海洋真菌产生的5-甲氧基杂色曲霉素的生物膜形成抑制活性
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[石田俊介, 荒井雅吉, 坪谷好恵, 小林資正]
通讯作者:
小林資正
海洋由来真菌が産生する新規アミノリポペプチドtrichoderin類の抗結核活性
海洋真菌产生的新型氨基脂肽木霉菌素的抗结核活性
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Patamaporn Pruksakorn, 荒井雅吉, 古徳直之, 小林資正]
通讯作者:
小林資正
海綿由来セスタテルペンheteroneminのbiofilm形成阻害活性
海绵来源的二倍萜异酮胺的生物膜形成抑制活性
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[韓智秀, 荒井雅吉, 石田俊介, 新川大貴, 小林資正]
通讯作者:
小林資正
共 44 条
Creation of novel molecular-targeted anticancer drugs focused on specific phenotypic changes of cells in tumor
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批准号:26242074
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$27.96万
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财政年份:2014
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负责人:KOBAYASHI Motomasa
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依托单位:
Development of short-step synthesis of probe molecules for accelerating target identification
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批准号:25560402
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.5万
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财政年份:2013
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负责人:KOBAYASHI Motomasa
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依托单位:
Establishment of in vivo screening system using Medaka fish toward to the drug discovery
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批准号:22659002
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$1.98万
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财政年份:2010
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负责人:KOBAYASHI Motomasa
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依托单位:
Search for Bioactive Natural Products for Molecular Target Chemotherapy of Cancer
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批准号:18201042
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$33.2万
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财政年份:2006
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负责人:KOBAYASHI Motomasa
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依托单位:
Investigation of Indonesian Marine Organisms as Medicinal Resources
-
批准号:15406005
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$8.32万
-
财政年份:2003
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负责人:KOBAYASHI Motomasa
-
依托单位:
Search for inhibitors of cell cycle and development for natural molecular probe
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批准号:15310148
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.86万
-
财政年份:2003
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负责人:KOBAYASHI Motomasa
-
依托单位:
Search for Indonesian Marine Life as Medicinal Resource (2)
-
批准号:11691208
-
项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$15.02万
-
财政年份:1999
-
负责人:KOBAYASHI Motomasa
-
依托单位:
Search for Reversing Agents of Multidrug-Resistance in Tumor Cells from Marine Organisms
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批准号:10680567
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.3万
-
财政年份:1998
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负责人:KOBAYASHI Motomasa
-
依托单位:
Search for New Anti-tumor Lead Compounds from Marine Organisms
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批准号:10557233
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$8.0万
-
财政年份:1998
-
负责人:KOBAYASHI Motomasa
-
依托单位:
Search for Indonesian Marine Life as Medicinal Resource
-
批准号:09041184
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项目类别:Grant-in-Aid for international Scientific Research
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资助金额:$8.45万
-
财政年份:1997
-
负责人:KOBAYASHI Motomasa
-
依托单位:
Pharmacochemical Investigation of Marine Sponge Products
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批准号:03671000
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.34万
-
财政年份:1991
-
负责人:KOBAYASHI Motomasa
-
依托单位:
海外基金