Development of a novel healing system for bone disease using a synergetic effect of magnetic fields and bone-regulating hormone

为了开发一种新的利用磁场治疗骨病的系统，我们使用体外测定系统研究了极低频（ELF）磁场（60 Hz）对金鱼鳞片成骨细胞和破骨细胞的影响。在体外实验中，金鱼鳞片中的成骨细胞和破骨细胞对ELF磁场敏感。结果与大鼠颅骨成骨细胞和破骨细胞的结果一致。此外，磁场和骨骼调节激素褪黑激素的协同作用也得到了证实。因此，我们成功地创建了一个新的治疗系统的骨疾病的磁场。

To develop a novel healing system for bone disease using magnetic fields, we examined the effects of extremely low-frequency(ELF) magnetic fields(60Hz) on osteoblasts and osteoclasts of goldfish scales using in vitro assay systems. The osteoblasts and osteoclasts in goldfish scales responded sensitively to the ELF magnetic fields in an in vitro experiment. The results agreed with those of rat calvarial osteoblasts and osteoclasts. In addition, the synergetic effect of magnetic fields and a bone-regulating hormone, melatonin, was confirmed. Thus, we succeeded in creating a novel healing system for bone disease by magnetic fields.