Role of PFR cells during digit identity determination.

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We found that the cells located distal to the digital lay received positional information from interdigit. These cells get BMP signaling from adjacent interdigit located at the posterior side. I named this region 'PFR'. We found that digit identity is controlled by physical flow in the interdigit, and this conclusion brings us new insight how morphogen gradient works in the embryos. Further, we identified single point mutation in Silkie chicken that causes preaxial polydactyly in the leg. We will publish this data in this May, in press now