Elucidating mechanisms of information processing of the brain during behavioral decision making using macro-brain membrane potential imaging

使用宏观脑膜电位成像阐明行为决策过程中大脑信息处理的机制

• 批准号: 23650222
• 负责人: SUZUKI Takayuki
• 金额: $ 2.16万
• 依托单位: The Institute of Physical and Chemical Research
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23650222/
• 关键词: 神経回路網; 大脳新皮質; 一次体性感覚野; 二次運動野; カラム; 膜電位イメージング; 行動実験; 1次体性感覚野; 2次運動野

The brain has many regions with their own distinct characteristics, and the interaction between these cortical regions causes various brain functions. In this study, using mice, I revealed that the primary somatosensory cortex which is an entrance of sensory information in the cerebral cortex receives a feedback input from secondary motor area, and this feedback input modulates the activity of primary somatosensory cortex and influences mouse behavior.

大脑有许多具有自己鲜明特点的区域，这些皮质区域之间的相互作用导致了不同的大脑功能。在这项研究中，我用小鼠揭示了初级体感皮质是大脑皮层中感觉信息的入口，从次级运动区接收反馈输入，该反馈输入调节初级体感皮质的活动，并影响小鼠的行为。