Development of tissue specific siRNA expression system to vascular endothelial cells in cancer
Development of tissue specific siRNA expression system to vascular endothelial cells in cancer
批准号:
21790161
负责人:
KOIZUMI Naoya
金额:
$2.75万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2010
中文摘要
点击翻译按钮获取中文摘要
英文摘要
We tried development of novel tissue specific siRNA expression system for cancer gene therapy by VSV-G lentivirus vector. Therefore, we substituted sequence of CCR5-siRNA in endogenous microRNA for driving by tissue specific promoter (RNA polymerase type II). As a result, the siRNA expression system had not worked by RNA polymerase type II promoter. We need further study for the development of tissue specific siRNA expression system.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
HIVイメージングシステムの開発
HIV成像系统的开发
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[小泉直也, Suree Tom, 清水佐紀, 渡辺善照, 安東星]
通讯作者:
安東星
DOI:
10.1182/blood-2009-04-215855
发表时间:
2010-02-25
期刊:
BLOOD
影响因子:
20.3
作者:
[Shimizu, Saki, Hong, Patrick, An, Dong Sung]
通讯作者:
An, Dong Sung
development of a therapeutic carrier protein for gene therapy
-
批准号:17K08464
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.0万
-
财政年份:2017
-
负责人:KOIZUMI Naoya
-
依托单位:
The development of protein delivery system through the cell membrane
-
批准号:25670082
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.41万
-
财政年份:2013
-
负责人:KOIZUMI Naoya
-
依托单位:
Basic Study of orally-delivered vaccine development using a new innate immunity inducer
-
批准号:23659086
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.41万
-
财政年份:2011
-
负责人:KOIZUMI Naoya
-
依托单位:
Development of fiber modified adenovirus vector
-
批准号:19790135
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.36万
-
财政年份:2007
-
负责人:KOIZUMI Naoya
-
依托单位:
海外基金