Structural studies on influenza viral RNA polymerase for designing new anti-viral drug

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As one of the measures to the menace of the new influenza virus appearance, I performed structural studies for designing new anti-influenza viral drug. Because a compound which can inhibit the function of viral RNA polymerase playing a central role in the replication of the influenza virus will be a good candidate, I solved a crystal structure of the RNA polymerase. In addition, using purified RNA polymerase in this study, I succeeded in the making of the antibody which suppressed a function of RNA polymerase. Drug development based on these results is expected in future.