Live-cell imaging of HIV replication component trafficking and assembly
Live-cell imaging of HIV replication component trafficking and assembly
批准号:
22390091
负责人:
MORIKAWA Yuko
金额:
$11.98万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
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英文摘要
Live-cell imaging revealed that Gag and GagPol proteins moved together with the transition from “confined” to “diffusive” and ”linear” movements. The linear movement was microtubule-based. The Gag/GagPol with the diffusive and linear movements were partially colocalized with some Rab and SNARE proteins. The RNA containing the Psi site, the signal for genome RNA packaging but not the RNA lacking the signal, was partially merged to Gag/GagPol. In the latter case, Gag/GagPol did not show a long linear movement.
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Overexpression of HRS induces BST-2 downregulation through its clathrin-binding domain.
HRS 的过度表达通过其网格蛋白结合域诱导 BST-2 下调。
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Hoshino Y, Okunaga H, Morikawa Y.]
通讯作者:
Morikawa Y.
Live cell imaging of influenza A virus hemagglutinin : dynamics on the apical plasma membrane and intracellular trafficking.
甲型流感病毒血凝素的活细胞成像:顶端质膜和细胞内运输的动态。
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Ohkura T, Momose F, Morikawa Y.]
通讯作者:
Morikawa Y.
Inhibitor of HIV-1 Gag assembly screened by yeast membrane-associated system
酵母膜相关系统筛选 HIV-1 Gag 组装抑制剂
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Urano E, Kuramochi N, Tomoda H, Takebe Y, Miyauchi K, Komano J, Morikawa Y]
通讯作者:
Morikawa Y
インフルエンザウイルスvRNP陽性リサイクリングエンドソームの極性輸送に関する宿主因子の機能解析
流感病毒vRNP阳性回收内体极性运输相关宿主因素的功能分析
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[百瀬文隆, 森川裕子]
通讯作者:
森川裕子
DOI:
10.1371/journal.pone.0047828
发表时间:
2012
期刊:
PloS one
影响因子:
3.7
作者:
[Haraguchi H, Noda T, Kawaoka Y, Morikawa Y]
通讯作者:
Morikawa Y
共 44 条
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