权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Effect of night and shift work on glucose tolerance-circadian rhythm of glucose tolerance and insulin resistance

夜班和倒班工作对糖耐量的影响——糖耐量和胰岛素抵抗的昼夜节律

基本信息

批准号：
16590520
负责人：
MORIKAWA Yuko
金额：
$ 2.3万
依托单位：
KANAZAWA MEDICAL UNIVERSITY
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2004
资助国家：
日本
起止时间：
2004 至 2005
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-16590520/
关键词：
shift work insulin resistance glucose tolerance metabolic syndrome serum lipid circadian rhythm 労働時間

项目摘要

The aims of this study were to investigate the influences of night and shift work on the markers of metabolic syndrome, such as glucose tolerance, and serum lipids. Thirty-three male factory workers were investigated. The sampling were carried out after each shift, daytime, evening and midnight.1. There were not any significant differences in the parameters of mean blood glucose level during several weeks, such as HbAlc, glycoalbumin, 1,5-anhydroglycitol among three shifts. The fasting insulin and HOMA-R of night and evening shifts were significantly higher than those of daytime shift.2. The level of triglyceride tended to be higher at night shift and evening shifts compared with daytime shift, but LDL-cholesterol and free fatty acid were higher at daytime shift compared with night and evening shifts.3. The blood pressure at night and evening shifts were significantly higher than those at daytime shift.4. The red blood cell counts, hematcrit, hemoglobin and platelet count at night and evening shifts were significantly higher than those of daytime shift.5. Total energy intake was not different among daytime shift, evening shift and night shift. However, intake of some foods, such as mushroom, potatoes, processed foods of soybean and green vegetables tend to be lower at night and evening shifts compared with daytime shift.6. The energy consumption at night and evening shifts were lower than that at daytime shift.

本研究的目的是调查夜班工作对代谢综合征标志物的影响，如葡萄糖耐量和血脂。调查了33名男性工厂工人。抽样是在白天、晚上和午夜的每个班次之后进行的。三班间几周平均血糖水平HbAlc、糖蛋白、1,5-无羟基糖醇等参数差异无统计学意义。夜班和晚班的空腹胰岛素和HOMA-R显著高于白班。夜班和晚班的甘油三酯水平比白班高，而白班的低密度脂蛋白胆固醇和游离脂肪酸水平比夜班和晚班高。夜班和晚班的血压明显高于白班。夜班和夜班患者的红细胞计数、红细胞压积、血红蛋白和血小板计数均显著高于白班。白班、晚班和夜班的总能量摄入无显著差异。然而，一些食物的摄入量，如蘑菇、土豆、大豆加工食品和绿色蔬菜，夜班和夜班的人往往比白班少。夜班和晚班的能耗均低于白班。