Assessment of Prevalence and Trends of Metabolic Syndrome among Bangladeshi Rural Women : From basic epidemiology to genetic screening

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Metabolic Syndrome (MS) has been replaced by 'global cardiometabolic risk, which is a complex disorder and an emerging clinical challenge. MS, defined as a constellation of cardiovascular disease (CVD) risk factors, is one of the growing public health burdens in the Asia-Pacific region, even though people in this region are no more overweight than Europeans and Americans. Comparative studies indicate that metabolic responses to obesity may be greater in South and East Asians than their western counterparts at given Body Mass Indexes (BMIs). But MS screening has only been done in a few countries of South East Asia, excluding Bangladesh. The present study was designed to conduct a comprehensive screening of metabolic syndrome in Bangladeshi rural women, including prevalence estimation and biomarker assessment. The clinical relevance of MS is that it identifies people who are at increased long-term risk of cardiovascular disease and type 2 Diabetes (T2DM), thus providing an opportunity for preventive lifestyle interventions.