The expression mechanism of protease activated receptors with inflammatory stimulations in intestinal myofibroblasts.
The expression mechanism of protease activated receptors with inflammatory stimulations in intestinal myofibroblasts.
批准号:
22580334
负责人:
SATO Koichi
金额:
$3.0万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
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英文摘要
The roles of PAR (protease activated receptor) in the intestinal myofibroblast do not fully understand. So, we designed this project to clarify the role of PAR and the control mechanisms of the expression of PAR in intestinal myofibroblasts. We found that the expression level of PAR in the whole cell by the stimulation with cytokines was not changed, but PAR was moved from membrane to cytosolic area. We also found that prostaglandin E2-induced cAMP is contributed in this mechanism.
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PGE2はPAR2の内在化によりPAR2機能を阻害する
PGE2 通过内化 PAR2 抑制 PAR2 功能
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[小松浩之, 円城寺秀平, 大浜剛, 佐藤晃一]
通讯作者:
佐藤晃一
DOI:
10.3748/wjg.v19.i17.2629
发表时间:
2013-05-07
期刊:
WORLD JOURNAL OF GASTROENTEROLOGY
影响因子:
4.3
作者:
[Kawasaki, Hideyoshi, Ohama, Takashi, Sato, Koichi]
通讯作者:
Sato, Koichi
マウス結腸筋線維芽細胞株の樹立とその有用性に関する検討
小鼠结肠肌成纤维细胞系的建立及其应用研究
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[川崎 秀吉, 大浜 剛, 佐藤 晃一]
通讯作者:
佐藤 晃一
マウス結腸筋線維芽細胞の遊走に対するSphingosine-1-Phosphateの影響
1-磷酸鞘氨醇对小鼠结肠肌成纤维细胞迁移的影响
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[小松浩之, 円城寺秀平, 大浜剛, 佐藤晃一, 川崎秀吉]
通讯作者:
川崎秀吉
DOI:
10.1016/j.lfs.2012.06.030
发表时间:
2012-08-21
期刊:
LIFE SCIENCES
影响因子:
6.1
作者:
[Komatsu, Hiroyuki, Shimose, Akihiro, Sato, Koichi]
通讯作者:
Sato, Koichi
Role of proton-sensing G protein-coupled receptors on microglial activation and neuronal cell survival in a mouse ischemia reperfusion model.
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批准号:15K06767
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.33万
-
财政年份:2015
-
负责人:SATO Koichi
-
依托单位:
Biochemical analysis of a DNA crosslink repair protein, FAN1
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批准号:26830128
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.5万
-
财政年份:2014
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负责人:SATO Koichi
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依托单位:
Role of proton-sensing G protein-coupled receptors on microglial activation and neuronal cell survival in a ischemic situation.
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批准号:24500435
-
项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.33万
-
财政年份:2012
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负责人:SATO Koichi
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依托单位:
Involvement of ABCA1 transporter in the regulation of anti-atherogenic sphingosine-1-phosphate content in plasma and high-density lipoprotein
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批准号:21591158
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.91万
-
财政年份:2009
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负责人:SATO Koichi
-
依托单位:
Combination of a membrane reactor and microwave radiation for high efficient chemical reaction
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批准号:21350085
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项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$12.56万
-
财政年份:2009
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负责人:SATO Koichi
-
依托单位:
A study of autobiographical memory system : effects of aging on the stability of remembering.
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批准号:20530586
-
项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.25万
-
财政年份:2008
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负责人:SATO Koichi
-
依托单位:
Downregulatory mechanism of protease activated receptor in inflammatory bowel disease
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批准号:19580340
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.0万
-
财政年份:2007
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负责人:SATO Koichi
-
依托单位:
Coupling of sphingosine 1-phosphate release with lipoprotein formation in central nervous system(CNS)
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批准号:18500287
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.57万
-
财政年份:2006
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负责人:SATO Koichi
-
依托单位:
Involvement of inflammatory cells on the dysmotility of gastrointestinal smooth muscles in experimental colitis model animals.
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批准号:15580260
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.43万
-
财政年份:2003
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负责人:SATO Koichi
-
依托单位:
Sphingosine 1-phosphate mediates some actions of lipoproteins that regulate neural functions.
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批准号:14580736
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.3万
-
财政年份:2002
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负责人:SATO Koichi
-
依托单位:
The research on the physical function of pore system formed by roots of the soil
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批准号:12660063
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.18万
-
财政年份:2000
-
负责人:SATO Koichi
-
依托单位:
Study on the precise observations of stellar and circum-stellar phenomena with the optical and infrared interferometer
-
批准号:10304015
-
项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$21.56万
-
财政年份:1998
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负责人:SATO Koichi
-
依托单位:
Studies on the macropore morphology of grassland soil determined by X-ray and contrast media.
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批准号:06660083
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.34万
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财政年份:1994
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负责人:SATO Koichi
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依托单位:
エルゴディク磁場形成に伴うRFPプラズマのエネルギー損失機構の研究
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批准号:04680012
-
项目类别:Grant-in-Aid for General Scientific Research (C)
-
资助金额:$1.22万
-
财政年份:1992
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负责人:SATO Koichi
-
依托单位:
Changes in properties of watershed and its conservation due to changes in land use in mountainous rural area
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批准号:04452295
-
项目类别:Grant-in-Aid for General Scientific Research (B)
-
资助金额:$4.42万
-
财政年份:1992
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负责人:SATO Koichi
-
依托单位:
Studies on a Novel Vasoactive Peptide, Endothelin, Derived from Vascular Endothelium.
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批准号:01480102
-
项目类别:Grant-in-Aid for General Scientific Research (B)
-
资助金额:$4.42万
-
财政年份:1989
-
负责人:SATO Koichi
-
依托单位:
Studies on the evaluation of influences of land reclamation on hydrologic cycle and the conservation in catchments
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批准号:62480075
-
项目类别:Grant-in-Aid for General Scientific Research (B)
-
资助金额:$4.67万
-
财政年份:1987
-
负责人:SATO Koichi
-
依托单位:
国内基金
海外基金
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脂噬介导的猪肌内脂肪(IMF)沉积调控及机制研究
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批准号:32372826
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项目类别:面上项目
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资助金额:50万元
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批准年份:2023
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负责人:陈小冬
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依托单位:
lnc-IMF通过结合miR-200b和HuR蛋白双重调控猪肌内脂肪沉积的机制研究
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批准号:32002147
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项目类别:青年科学基金项目
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资助金额:24.0万元
-
批准年份:2020
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负责人:李伯江
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利用跨极区极光弧形态北向IMF条件下变形的地球磁层中的等离子体诊断
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批准号:42074194
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项目类别:面上项目
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资助金额:60.0万元
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批准年份:2020
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负责人:Motoharu Nowada
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依托单位:
核转运蛋白IMF调控胚珠发育的分子机理研究
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批准号:31871422
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项目类别:面上项目
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资助金额:60.0万元
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批准年份:2018
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烟酸调控湘中黑牛肌内脂肪(IMF)沉积的机理研究
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批准号:31402100
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影响新疆地方品种驴肉IMF沉积的基因筛选及其启动子区甲基化差异研究
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批准号:31360530
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负责人:曾维斌
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拜城油鸡H-FABP基因多态性及其mRNA表达量与IMF含量相关性研究
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资助金额:50.0万元
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批准年份:2011
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依托单位:
高纬电离层对流的SuperDARN雷达研究-对瞬变IMF的响应及与亚暴的关系
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批准号:40504019
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项目类别:青年科学基金项目
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资助金额:26.0万元
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批准年份:2005
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负责人:徐良
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依托单位: