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The mechanism by which rikkunshito increases acylated ghrelin

The mechanism by which rikkunshito increases acylated ghrelin
rikkunshito 增加酰化 ghrelin 的机制
批准号:
22590676
负责人:
TAKEDA Hiroshi
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012

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中文摘要
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英文摘要
This study was conducted to uncover the mechanism by which rikkunshito increases plasma acylatedto desacyl-ghrelin ratio in cisplatin-treated rats. Several components of rikkunsito including 10-gingeroldemonstrated inhibitory activity against ghrelin deacylating enzyme, carboxylesterase. Furthermore,stably transfected GOAT/ preproghrelin HEK 293 cells were successfully established to explore theeffects of rikkunshito on ghrelin producing machinery.
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会议论文
Impaired Gastric Emptying in Gastroesophageal Reflux Disease Rat Models is Caused by a Reduced Response to Ghrelin.
胃食管反流病大鼠模型中胃排空受损是由生长素释放肽反应降低引起的。
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Takeda H, Muto S, Oridate N, Ohnishi S, Nakagawa K, Sadakane C, Saegusa Y, Nahata M, Sadakane C, Hattori T, Asaka M.]
通讯作者: Asaka M.
Social Isolation After Anorexia is Mediated by Abnormalities in Serotonin 2C Receptor Reactivity.
厌食症后的社会孤立是由 5-羟色胺 2C 受体反应异常介导的。
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [Sadakane C, Takeda H, Saegusa Y, Hattori T, Nakagawa K, Muto S, Asaka M.]
通讯作者: Asaka M.
食欲の科学
食欲科学
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [Takuzo Hano, Tetsuya Kawabe, 平田 喜裕, Saiki I, Hayakawa Y, 武田宏司]
通讯作者: 武田宏司
六君子湯の食欲改善作用のメカニズム
六君子汤改善食欲作用的机制
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [武田宏司, 武藤修一, 大西俊介]
通讯作者: 大西俊介
38
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