Development of multi-modality circumferential sensor array andthe analysis of esophageal motility

我们开发了一种多模态环形传感器阵列，其中有8个pH和8个压力传感器，分布在8个不同的方向，用于评估食管-胃交界处的食管收缩和胃-食管酸反流。我们也发展了食管-胃交界处的形态测量诊断与320排CT。通过这两种方法，我们发现胃食管反流可以分为两种类型。其中之一是与短暂性食管下括约肌松弛有关的容积反流。这种类型的反流常伴有第二次蠕动，并伴有容积清除。另一种类型的反流是由小体积反流引起的爬行反流，主要发生在食管右前壁。本研究发现的这些信息有助于深入了解胃食管反流的机制。

We have developed a multi-modality circumferential sensor array with 8 pH and 8 pressure sensors arranged in 8 different directions for evaluating esophageal contraction and gastro-esophageal acid reflux at the esophago-gastric junction. We have also developed a morph metrical diagnosis on esophago-gastric junction with a 320 row CT. With these two methods, we have found that the gastro-esophageal reflux can be divided in two types. One of them is the volume reflux related with transient lower esophageal sphincter relaxation. This type of reflux is frequently accompanied by the secondly peristalsis with volume clearance. The other type of reflux is the creeping reflux caused by the small volume reflux that occurs mainly on the right anterior wall of the esophagus. Thisinformation found in this study facilitates the thorough understanding of the mechanism of gastro-esophageal reflux.