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The association between genetic variations of the neuronal nicotinic cholinergic receptors and smoking-related lung diseases

The association between genetic variations of the neuronal nicotinic cholinergic receptors and smoking-related lung diseases
神经元烟碱胆碱能受体的遗传变异与吸烟相关肺部疾病之间的关联
批准号:
22590845
负责人:
KIDA Kozui
金额:
$3.0万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012

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中文摘要
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英文摘要
The study population comprised 366 current or ex-smokers including 247 COPD patients. Two of the SNPs, rs3743078 and rs660652, in CHRNB4-CHRNA3-CHRNA5 showed an association with %LAA in the upper region of the lungs (p = 0.0050 and 0.0038, respectively) and were also associated with the mRNA expression of CHRNA3 and CHRNA5. CHRNA3 was expressed also in the lung, confirmed pathologically.
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Association between emphysema and genetic variations of CHRNA3
肺气肿与 CHRNA3 遗传变异之间的关联
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Takeo Ishii, Kozui Kida, 他]
通讯作者:
A STUDY OF ALTERATIONS OF PLEURAL STRUCTURE BY GROWTH,DEVELOPMENT AND AGING.
MORPHOLOGICAL CHANGES OF ALVEOLAR CAPILLARY CONFIGURATIONS IN GROWING LUNG.
  • 批准号:
    05670543
  • 项目类别:
    Grant-in-Aid for General Scientific Research (C)
  • 资助金额:
    $0.45万
  • 财政年份:
    1993
  • 负责人:
    KIDA Kozui
  • 依托单位:
Observation of lung injury and repair during growth and development in rats
  • 批准号:
    03670410
  • 项目类别:
    Grant-in-Aid for General Scientific Research (C)
  • 资助金额:
    $1.15万
  • 财政年份:
    1991
  • 负责人:
    KIDA Kozui
  • 依托单位:
Study of Compensatory Lung Growth Following Pneumonectomy on Rats.
  • 批准号:
    01570437
  • 项目类别:
    Grant-in-Aid for General Scientific Research (C)
  • 资助金额:
    $1.34万
  • 财政年份:
    1989
  • 负责人:
    KIDA Kozui
  • 依托单位:
海外基金