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Alteration of tumor immunity and anti-cancer drug / hormone sensitivity accompanied by MMR mechanism abnormality in endometrial cancer

Alteration of tumor immunity and anti-cancer drug / hormone sensitivity accompanied by MMR mechanism abnormality in endometrial cancer
子宫内膜癌伴随MMR机制异常的肿瘤免疫及抗癌药物/激素敏感性改变
批准号:
22591867
负责人:
SUSUMU Nobuyuki
金额:
$2.83万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012

项目摘要

项目成果

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中文摘要
翻译
我们发现,那些浸润性调节性T细胞(Treg)较多的子宫内膜癌病例是明显低分化或晚期癌症,预后不良,而那些Treg/CD 8比值较高的病例,其预后不良。
英文摘要
We detected that those cases with endometrial cancer with many infiltrative regulatory T cells (Treg) were significantly poorly-differentiated or advanced-stage cancer and had poor prognosis, and that those cases with high Treg/CD8 ratio had poor prognosi
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会议论文
DOI: 10.3892/or.2012.1912
发表时间: 2012-10
期刊: Oncology reports
影响因子: 4.2
作者: [Masuda K, Banno K, Yanokura M, Tsuji K, Kobayashi Y, Kisu I, Ueki A, Yamagami W, Nomura H, Tominaga E, Susumu N, Aoki D]
通讯作者: Aoki D
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [Susumu N, Saito E, Nomura H, et al]
通讯作者: et al
Complete remission of recurrent and refractory uterine epithelioid leiomyosarcoma using weekly administration of bevacizumab and temozolomide
每周给予贝伐珠单抗和替莫唑胺可完全缓解复发性难治性子宫上皮样平滑肌肉瘤
DOI: 10.1016/j.ejogrb.2011.02.020
发表时间: 2011
期刊: Eur J Obstet Gynecol Reprod Biol.
影响因子: --
作者: [Takano M, Kikuchi Y, Susumu N, et al]
通讯作者: et al
How long can young women with endometrial cancer be safely treated with MPA for fertility-preserving?-from a retrospective analysis of 88 cases-
年轻子宫内膜癌女性接受MPA保育多久可以安全?-来自88例的回顾性分析-
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Susumu N, Yamagami Y, Ichikawa Y, et al]
通讯作者: et al
59
    Relation between alteration of DNA mismatch repair/tumor immunologyand sensitivities of anti-cancer drugs and hormone in endometrialcancer
    • 批准号:
      19591943
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.91万
    • 财政年份:
      2007
    • 负责人:
      SUSUMU Nobuyuki
    • 依托单位:
    Correlation of microsatellite instability (MSI) and sensitivity for anti-cancer drugs in endometrial cancer
    • 批准号:
      15591778
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.3万
    • 财政年份:
      2003
    • 负责人:
      SUSUMU Nobuyuki
    • 依托单位:
    海外基金