Telomerase-Specific Replication-Selective Virotherapy combined with radiation therapy for oral squamous cell carcinoma cells.
Telomerase-Specific Replication-Selective Virotherapy combined with radiation therapy for oral squamous cell carcinoma cells.
批准号:
22792013
负责人:
KURIHARA Yuji
金额:
$2.5万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011
中文摘要
我们描述了辐射和病毒治疗协同作用的机制基础。这种联合治疗在OSCC细胞中比单独使用端粒溶酶更有效。这些结果说明了溶瘤病毒治疗和电离辐射联合治疗作为治疗人类口腔癌的一种有前途的策略的潜力。
英文摘要
We describe the mechanistic basis for synergy of irradiation and virotherapy. This combination therapy was more effective compared with Telomelysin alone in OSCC cells. These results illustrate the potential of combining oncolytic virotherapy and ionizing radiation as a promising strategy in the management of human oral cancer.
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专著(0)
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会议论文
Telomerase-Specific Replication-Selective Virotherapy combined with radiation therapy for oral squamous cell carcinoma cells
端粒酶特异性复制选择性病毒治疗联合放射治疗口腔鳞状细胞癌细胞
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Sato H, Saisu H, Muraoka W, Nakagawa T, Svensson P, Wajima K., Yuji Kurihara]
通讯作者:
Yuji Kurihara
Regulation of PirB, a receptor causing neurodegenerative diseases
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批准号:16K21268
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.66万
-
财政年份:2016
-
负责人:KURIHARA Yuji
-
依托单位:
Regulation of PirB, a functional receptor for axonal growth inhibitors, by LOTUS
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批准号:26870480
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.5万
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财政年份:2014
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负责人:KURIHARA Yuji
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依托单位:
Antitumor effects of telomerase-specific replication-selective oncolytic viruses for adenoid cystic carcinoma cell lines.
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批准号:24792254
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.66万
-
财政年份:2012
-
负责人:KURIHARA Yuji
-
依托单位:
Mechanism of neurite outgrowth promoting effect of LOTUS, an antagonist for Nogo receptor
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批准号:24890187
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项目类别:Grant-in-Aid for Research Activity Start-up
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资助金额:$1.66万
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财政年份:2012
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负责人:KURIHARA Yuji
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依托单位:
海外基金