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The dental trial and its molecular biological analysis to promotion of a move as reform study by multi-blood platelet plasma(PRP)

The dental trial and its molecular biological analysis to promotion of a move as reform study by multi-blood platelet plasma(PRP)
多血血小板血浆(PRP)推动改革研究的牙科试验及其分子生物学分析
批准号:
22792058
负责人:
FUJIMURA Yuji
金额:
$2.58万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011
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中文摘要
翻译
我听说牙科正畸治疗的基础是将正畸力施加到牙齿上,是有的,这些基础是不会改变的。虽然美观性的提高、剧烈疼痛的减轻、清洁的简化等被提到是牙科正畸治疗的主题,但将治疗期缩短到治疗期也是一大主题。医疗效率的提高是通过各种材料的发展、近年来的力学研究和缩短治疗期来实现的。然而,不能说效果仍然足够。尽管牙科正畸治疗使用生命反应进行医学治疗,但大多数针对活体本身的方法都没有进行,但人们认为通过控制生命反应来缩短进一步的治疗期。它的目标是…为了什么本研究应用了更多的骨科等牙科领域,利用小鼠牙齿在多血小板血浆(PRP‘s)中移动的实验模型,以提高牙齿移动效率为例,研究了PRP对牙齿移动的影响。它配备了闭合螺旋弹簧,将小鼠上切牙部分的牙槽骨与左侧的第一磨牙之间,并进行了第一磨牙的邻里移动。从同基因小鼠的心脏,PRP收集血液并将其离心化。将激活剂混合到左侧第一磨牙颊侧皮下部分,并在牙齿移动开始时对其激活的PRP被注射。12天后使用义齿用硅胶印模材料,取上颌骨印模,在物质显微镜下测量第一磨牙和第二磨牙间的距离,作为牙齿的移动量。在PRP用药组和PBS用药组(对照组)中,牙齿活动量没有明显差异,但由于PRP的最佳剂量尚不清楚,似乎从现在开始首先需要检查最佳给药剂量。较少
英文摘要
I hear that the base of a dentistry orthodontic therapy applies and moves orthodontic force to a tooth, there is, and these foundations do not change. Although improvement in aesthetic appreciation nature, mitigation of sharp pain, simplification of cleaning, etc. are mentioned as a subject of a dentistry orthodontic therapy, shortening of the length of the treatment period to a treatment period is also one of the big subjects.The increase in efficiency of medical treatment is made by development of various materials, and research of mechanics in recent years, and shortening of a treatment period has come to be achieved. However, it cannot be said that the effect is still enough. In spite of the medical treatment for which the dentistry orthodontic therapy used the vital reaction, most approaches against the living body itself are not performed, but it is thought that shortening of the further treatment period is attained by controlling a vital reaction. It aims at the thing for which … More orthopedics and other dentistry fields are used and which obtain fundamental evidence using the experiment model of movement of the tooth of a mouse in multi-blood platelet plasma(PRP's) using and using the dental increase in efficiency of movement as figure wax in this research.The effect of PRP to dental movement was examined. It equipped with the closed coil spring of the upper incisor part alveolar bone of a mouse, and between the first molar of left-hand side, and carried out too the neighborhood movement of the first molar. From the heart of the syngeneic mouse, PRP collected blood and it centrifuged it. PRP which mixed the activator to the left-hand side first-molars cheek side subcutaneous part, and was activated to it at the time of a dental move start was injected. The silicone impression material for dentistries was used 12 days afterward, the upper jaw was impression taking, the first molar and the distance between the second molar were measured under the substance microscope, and it was considered as the dental amount of movements. In the PRP medication group and the PBS medication group(contrast group), the significant difference was not observed in the dental amount of movements.However, since optimal quantity of PRP is unknown, it seems first that examination is required about a optimal given dose from now on. Less
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A trial study to acceleration of orthodontic tooth movement by low intensity pulsed ultrasound
  • 批准号:
    24593100
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $3.33万
  • 财政年份:
    2012
  • 负责人:
    FUJIMURA Yuji
  • 依托单位:
The effect of cathepsin E on orthodontic tooth movement
  • 批准号:
    20791585
  • 项目类别:
    Grant-in-Aid for Young Scientists (B)
  • 资助金额:
    $2.75万
  • 财政年份:
    2008
  • 负责人:
    FUJIMURA Yuji
  • 依托单位:
海外基金