Design of Metalloproteins based on principal of inter-element chemistry
Design of Metalloproteins based on principal of inter-element chemistry
批准号:
22750156
负责人:
MATSUO Takashi
金额:
$2.25万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011
中文摘要
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英文摘要
Some artificial metalloproteins were successfully constructed from the aspects of "fashions of metal coordination","inter-element principal(interactions between elements)" and "structural characteristics of proteins". An organometallic artificial protein with a C-coordinated metal center was prepared through inhibition mechanism of serine proteases. Furthermore, we successfully develop a protein structure-based switching system of emission property of a metal complex attached onto the surface the protein. We also found autoreduction of a copper ion with S-coordination, which was constructed at the active site of a chemically modified subtilisin.
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Creation of Artificial Organometallic Enzyme by Using Intrinsic Mechanism of Parent Protein
利用母体蛋白的内在机制创建人工有机金属酶
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Takashi Matsuo, Chie Imai, Takefumi Yoshida, Akira Fujii, Takashi Saito, Takashi Hayashi, Shun Hirota]
通讯作者:
Shun Hirota
プロテアーゼの機能メカニズムに基づく有機金属錯体含有タンパク質の創成
基于蛋白酶的功能机制创建含有机金属复合物的蛋白质
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[吉田武史, 松尾貴史, 今井千絵, 廣田俊]
通讯作者:
廣田俊
DOI:
10.1039/c1ob05552f
发表时间:
2011-06
期刊:
Organic & biomolecular chemistry
影响因子:
3.2
作者:
[Zhonghua Wang;T. Matsuo;S. Nagao;S. Hirota]
通讯作者:
Zhonghua Wang;T. Matsuo;S. Nagao;S. Hirota
サブチリシン活性部位の化学修飾に基づくシステイン配位銅錯体の構築
基于枯草杆菌蛋白酶活性位点化学修饰的半胱氨酸配位铜配合物的构建
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[権田勝也, 松尾貴史, 廣田俊]
通讯作者:
廣田俊
DNA Cleavage by Photo-Controlled Cooperation of Zn(II) Centers in Azobenzene-Linked Dizinc Complex
偶氮苯连接的二锌复合物中 Zn(II) 中心的光控合作进行 DNA 切割
DOI:
--
发表时间:
2011
期刊:
Inorg. Chem.
影响因子:
4.6
作者:
[Anangamohan Panja, Takashi Matsuo, Satoshi Nagao, Shun Hirota]
通讯作者:
Shun Hirota
共 12 条
Development of a new approach to the treatments in conservative dentistry based on a concept for home or visit care.
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批准号:17K11708
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Application of electromagnetic wave irradiation to deep caries lesion.
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财政年份:2014
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Functional analysis of odorant and gustatory receptors in insects
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批准号:24380030
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Clarification of action mechanism of caspase-activating molecules and cancer cell-selective induction of apoptosis
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批准号:24550189
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.58万
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财政年份:2012
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Blood flow velocity profiles in the middle cerebral artery during cycle exercise and physical work.
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批准号:24500479
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.33万
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财政年份:2012
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Development of a new comprehensive treatment for dental caries based on minimum intervention dentistry
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批准号:23390435
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.23万
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财政年份:2011
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负责人:MATSUO Takashi
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依托单位:
The biological role of odorant-binding proteins in insect behavior
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批准号:21688003
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项目类别:Grant-in-Aid for Young Scientists (A)
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资助金额:$7.82万
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财政年份:2009
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负责人:MATSUO Takashi
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依托单位:
Measurement and analysis of blood flow velocity waveforms in the middle cerebral artery under posture change and exercise.
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批准号:20500401
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.0万
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财政年份:2008
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负责人:MATSUO Takashi
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依托单位:
Development of the diagnosis and treatment of root caries on its pathosis and pathogenesis
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批准号:20592229
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.91万
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财政年份:2008
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负责人:MATSUO Takashi
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依托单位:
Research on International Comparison about Architectures of Service Industry
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批准号:20530350
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资助金额:$3.0万
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财政年份:2008
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Evolution of host plant selection in Drosophila
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批准号:19770210
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.19万
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财政年份:2007
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负责人:MATSUO Takashi
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Investigation on the reaction mechanism of heme oexygenase having non-natural tetrapyrrolic cofactors
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批准号:19750142
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.43万
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依托单位:
Analysis of bacterial invasive lesion of refractory periapical periodontitis cases by genetic engineering technique
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批准号:18592092
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Development of the new diagnostic methods and treatments of dental caries based upon caliology
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批准号:14207081
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资助金额:$31.87万
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财政年份:2002
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依托单位:
Identification of the gene responsible for host-plant selection in Drosophila sechellia
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批准号:13640617
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.98万
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财政年份:2001
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负责人:MATSUO Takashi
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依托单位:
A histological investigation into the actual conditions of infected regions of apices of the teeth with apical periodontitis
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批准号:12671853
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.5万
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财政年份:2000
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负责人:MATSUO Takashi
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依托单位:
Fractal patterns in nature and feelings
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批准号:10835006
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.11万
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财政年份:1998
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负责人:MATSUO Takashi
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依托单位:
Bacterial Invasion of Infected Canals and Root Dentin of Human Teeth and Analysis of the Host-parasite Interaction at the Apex. - Elucidation of Pathogenesis of Refractory Cases-.
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批准号:10470406
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$6.21万
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财政年份:1998
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负责人:MATSUO Takashi
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依托单位:
Application of fractal geometry to pathological morphology.
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批准号:02807039
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.02万
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财政年份:1990
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负责人:MATSUO Takashi
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依托单位:
On the importance of vascular architecture in selective vulnerability of the basal ganglia.
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批准号:63570154
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.34万
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负责人:MATSUO Takashi
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依托单位:
海外基金