Analysis of bone morphogenesis using human dental pulp as biomaterial

以人牙髓为生物材料的骨形态发生分析

• 批准号: 22592190
• 负责人: ITO Katsutoshi
• 金额: $ 2.83万
• 依托单位: Health Sciences University of Hokkaido
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22592190/
• 关键词: ヒト歯髄; BMP; 骨形成; fg-Hap; ヒト脱灰象牙質 (DDM)脱灰象牙質 (DDM); 硬組織再生; ヒト脱灰象牙質

It was analyzed the tissue regeneration factor included in the human pulp tissue and dentin for reusing as biomaterial. In the result, it was revealed there existed many hard tissue relative factors and tissue regeneration factors in addition to BMPs, strong bone morphogenetic factor. It was affirmed that the materials using as carriers for dental pulp included BMP-2 and BMP-7, it was suggested they were useful as hard tissue regeneration.

分析了人牙髓组织和牙本质中所含的组织再生因子，以供作为生物材料再利用。结果表明，除骨形态发生因子BMPs外，还存在许多硬组织相关因子和组织再生因子。证实BMP-2和BMP-7是牙髓组织再生的载体材料，可作为硬组织再生的载体材料。

项目成果

Surface Characteristics and Osteoinductivity of Biomimetic Ceramic Scaffolds

仿生陶瓷支架的表面特性和骨诱导性

• 发表时间: 2012
• 作者: Junichi Tazaki;Katsutoshi Ito
• 通讯作者: Katsutoshi Ito

ヒト歯髄組織における肝細胞増殖因子の発現

肝细胞生长因子在人牙髓组织中的表达

• 发表时间: 2010
• 作者: 伊藤勝敏;村田勝;有末眞;ら
• 通讯作者: ら

In vivo evaluation of a novel chitosan/HAp composite biomaterial as a carrier of rhBMP-2

新型壳聚糖/HAp复合生物材料作为rhBMP-2载体的体内评价

• 发表时间: 2010
• 期刊: Journal of Hard Tissue Biology
• 影响因子: 0.4
• 作者: 柏崎晴彦;村田勝
• 通讯作者: 村田勝

Multinucleated Giant Cells for Biomaterials - Ceramics and Dentin Collagen -

用于生物材料的多核巨细胞 - 陶瓷和牙本质胶原 -

• DOI: 10.4028/www.scientific.net/kem.493-494.310
• 发表时间: 2011
• 期刊: Key Engineering Materials
• 作者: M. Murata;T. Akazawa;J. Hino;J. Tazaki;K Ito;M. Fujii;T. Shibata;M. Arisue
• 通讯作者: M. Arisue

Single standing implant in the region of immediate autograft of demineralized dentin matrices for bone augmentation

用于骨增量的脱矿牙本质基质即刻自体移植区域中的单立式种植体

• 发表时间: 2010
• 作者: Katsutoshi Ito;Masaru Murata
• 通讯作者: Masaru Murata